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    ChemeGen ChemeGen BRD5648 纯度:98% CAS:2056261-42-6 (5mg/瓶) C109838 2056261-42-6
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    ¥7670
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    BRD5648 ((R)-BRD0705) is an inactive (R)-enantiomer of BRD0705. BRD0705 is a potent, paralog selective and orally active GSK3α inhibitor with an IC50 of 66 nM and a Kd of 4.8 μM. BRD0705 displays increased selectivity for GSK3α (8-fold) versus GSK3β (IC50 of 515 nM). BRD0705 can be used for acute myeloid leukemia (AML).