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ChemeGen ChemeGen KB02-JQ1 纯度:98% CAS:2384184-44-3 (5mg/瓶) C110236 2384184-44-3
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¥11210
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敏感偏远地区（云南、新疆、西藏、内蒙古、青海、海南、宁夏）不支持交易
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KB02-JQ1 is a highly selective and PROTAC-based BRD4 degrader (molecular glue), but does not degrade BRD2 or BRD3. KB02-JQ1 promotes BRD4 degradation by covalently modifying DCAF16 (E3 ligase) and can improve the durability of protein degradation in biological systems. JQ1 binds ubiquitin E3 ligase ligand KB02 via a linker to form KB02-JQ1.
