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ChemeGen ChemeGen DT2216 纯度:98% CAS:2365172-42-3 (1mg/瓶) C110261 2365172-42-3
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¥10620
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DT2216 is a potent and selective BCL-XL degrader based on PROTAC technology. SIAIS178 causes effective degradation of BCL-XL protein by recruiting Von Hippel-Lindau (VHL) E3 ubiquitin ligase. DT2216 inhibits various BCL-XL-dependent leukemia and cancer cells but considerably less toxic to platelets.
