化合物简介
Pentamidine (formulated as a salt, pentamidine diisethionate or dimesilate) is an antimicrobial medication given to prevent and treat pneumocystis pneumonia (PCP) caused by Pneumocystis jirovecii (formerly named Pneumocystis carinii), a severe interstitial type of pneumonia often seen in patients with human immunodeficiency virus (HIV) infection. The drug is also the mainstay of treatment for stage I infection with Trypanosoma brucei gambiense (West African trypanosomiasis).
基本信息
中文名称
喷他脒
英文名称
pentamidine
中文别名
4,4\'-二脒基二苯氧基戊烷
英文别名
Pentamidine、4,4\'-(Pentane-1,5-diylbis(oxy))dibenzimidamide
CAS号
100-33-4
分子式
C19H24N4O2
分子量
340.419
精确质量
340.19
PSA
118.2
LOGP
4.4829
编号系统
EINECS号
202-841-0
物化性质
外观与性状
橙色固体
密度
1.2g/cm3
沸点
539.4ºC at 760mmHg
熔点
186ºC (dec.)
闪点
280ºC
稳定性
Stable under normal temperatures and pressures.
储存条件
Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
蒸汽压
1.06E-11mmHg at 25°C
安全信息
危险品运输编码
UN 3249
海关编码
2925290090
危险类别
6.1(b)
包装等级
III
