百科

alpha,alpha-二氟胸苷

alpha,alpha-二氟胸苷

CAS号：101527-46-2

英文名：5-(difluoromethyl)-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione

分子式：C10H12F2N2O5

分子量：278.209

上游原料

3',5'-bis-O-(tert-butyldiphenylsilyl)-5-bromomethyl-2'-deoxyuridine

3',5'-bis-O-(tert-butyldiphenylsilyl)-5-bromomethyl-2'-deoxyuridine

3',5'-di-O-(tert-butyldiphenyl)silyl-2'-deoxy-5-formyluridine

3',5'-di-O-(tert-butyldiphenyl)silyl-2'-deoxy-5-formyluridine

3',5'-di-O-(tert-butyldiphenyl)silyl-α-hydroxythymidine

3',5'-di-O-(tert-butyldiphenyl)silyl-α-hydroxythymidine

3',5'-bis-O-(tert-butyldiphenylsilyl)-thymidine

3',5'-bis-O-(tert-butyldiphenylsilyl)-thymidine

5'-O-TBDPS-dT

3',5'-di-O-(tert-butyldiphenyl)silyl-α,α-difluorothymidine

3',5'-di-O-(tert-butyldiphenyl)silyl-α,α-difluorothymidine

上游原料

3',5'-bis-O-(tert-butyldiphenylsilyl)-5-bromomethyl-2'-deoxyuridine 3',5'-di-O-(tert-butyldiphenyl)silyl-2'-deoxy-5-formyluridine 3',5'-di-O-(tert-butyldiphenyl)silyl-α-hydroxythymidine 胸苷 3',5'-bis-O-(tert-butyldiphenylsilyl)-thymidine 5'-O-TBDPS-dT 3',5'-di-O-(tert-butyldiphenyl)silyl-α,α-difluorothymidine