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Largazole thiol

Largazole thiol

CAS号：1033814-08-2

英文名：Largazole thiol

分子式

C21H28N4O4S3

熔点

密度

分子量

496.666

沸点

溶解度

信号词

危险品标志

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基本信息

中文名称

Largazole thiol

英文名称

Largazole thiol

中文别名

英文别名

(5R,8S,11S)-8-isopropyl-11-((E)-4-mercaptobut-1-en-1-yl)-5-methyl-10-oxa-3,17-dithia-7,14,19,20-tetraazatricyclo [14.2.1.12,5]icosa-1(18),2(20),16(19)-triene-6,9,13-trione、largazole thiol

CAS号

1033814-08-2

分子式

C21H28N4O4S3

分子量

496.666

精确质量

496.127

PSA

202.09

LOGP

2.437

合成路线

(S,E)-2-(trimethylsilyl)ethyl 3-(((S)-2-((((9H-fluoren-9-yl)methoxy)carbonyl) amino)-3-methylbutanoyl)oxy)-7-(tritylthio)hept-4-enoate

(S,E)-2-(trimethylsilyl)ethyl 3-(((S)-2-((((9H-fluoren-9-yl)methoxy)carbonyl) amino)-3-methylbutanoyl)oxy)-7-(tritylthio)hept-4-enoate

Largazole thiol

Largazole thiol

上游原料

共找到4个上游原料 >

(12Z,22Z,24R,5S,8S)-5-isopropyl-24-methyl-8-vinyl-24,25-dihydro-7-oxa-4,11-diaza-1(4,2),2(2,4)-dithiazolacyclododecaphane-3,6,10-trione

(12Z,22Z,24R,5S,8S)-5-isopropyl-24-methyl-8-vinyl-24,25-dihydro-7-oxa-4,11-diaza-1(4,2),2(2,4)-dithiazolacyclododecaphane-3,6,10-trione

(3S,4E)-3-hydroxy-1-((4R)-4-isopropyl-2-thioxothiazolidin-3-yl)-7-tritylsulfanyl-hept-4-en-1-one

(3S,4E)-3-hydroxy-1-((4R)-4-isopropyl-2-thioxothiazolidin-3-yl)-7-tritylsulfanyl-hept-4-en-1-one

(S,E)-2-(trimethylsilyl)ethyl 3-(((S)-2-((((9H-fluoren-9-yl)methoxy)carbonyl) amino)-3-methylbutanoyl)oxy)-7-(tritylthio)hept-4-enoate

(S,E)-2-(trimethylsilyl)ethyl 3-(((S)-2-((((9H-fluoren-9-yl)methoxy)carbonyl) amino)-3-methylbutanoyl)oxy)-7-(tritylthio)hept-4-enoate

(12Z,22Z,24R,5S,8S)-8-((E)-4-(tert-butyldisulfaneyl)but-1-en-1-yl)-5-isopropyl-24-methyl-24,25-dihydro-7-oxa-4,11-diaza-1(4,2),2(2,4)-dithiazolacyclododecaphane-3,6,10-trione

(12Z,22Z,24R,5S,8S)-8-((E)-4-(tert-butyldisulfaneyl)but-1-en-1-yl)-5-isopropyl-24-methyl-24,25-dihydro-7-oxa-4,11-diaza-1(4,2),2(2,4)-dithiazolacyclododecaphane-3,6,10-trione

上游原料

(12Z,22Z,24R,5S,8S)-5-isopropyl-24-methyl-8-vinyl-24,25-dihydro-7-oxa-4,11-diaza-1(4,2),2(2,4)-dithiazolacyclododecaphane-3,6,10-trione (3S,4E)-3-hydroxy-1-((4R)-4-isopropyl-2-thioxothiazolidin-3-yl)-7-tritylsulfanyl-hept-4-en-1-one (S,E)-2-(trimethylsilyl)ethyl 3-(((S)-2-((((9H-fluoren-9-yl)methoxy)carbonyl) amino)-3-methylbutanoyl)oxy)-7-(tritylthio)hept-4-enoate (12Z,22Z,24R,5S,8S)-8-((E)-4-(tert-butyldisulfaneyl)but-1-en-1-yl)-5-isopropyl-24-methyl-24,25-dihydro-7-oxa-4,11-diaza-1(4,2),2(2,4)-dithiazolacyclododecaphane-3,6,10-trione