化合物简介
Dexpramipexole (KNS-760704) is a drug that was investigated by Knopp Biosciences and Biogen Idec for the treatment of amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig’s disease. The drug failed to show efficacy in terms of function or survival in a Phase III study of patients with ALS.
基本信息
中文名称
R-普拉克索
英文名称
(6R)-6-N-propyl-4,5,6,7-tetrahydro-1,3-benzothiazole-2,6-diamine
中文别名
(R)-普拉克索二盐酸化物、(R)-普拉克索
英文别名
(6R)-2-amino-4,5,6,7-tetrahydro-6-(propylamino)benzothiazole、Dexpramipexole、(R)-N6-propyl-4,5,6,7-tetrahydrobenzo[d]thiazole-2,6-diamine、(6R)-4,5,6,7-tetrahydro-N6-propylbenzothiazole-2,6-diamine、(R)-Pramipexole Dihydrochloride、Pramipexole [USAN:INN]、(R)-(+)-2-amino-4,5,6,7-tetrahydro-6-(n-propylamino)benzothiazole
CAS号
104632-28-2
分子式
C10H19Cl2N3S
分子量
284.249
精确质量
283.068
PSA
83.52
LOGP
4.3849
物化性质
熔点
270-272ºC
安全信息
海关编码
2934999090
