百科

(3S,4R)-3-<(1R)-(tert-butyldimethylsiloxy)ethyl>-4-<5-(p-nitrobenzyloxycarbonylamino)pentanoylthio>azetidin-2-one

(3S,4R)-3-<(1R)-(tert-butyldimethylsiloxy)ethyl>-4-<5-(p-nitrobenzyloxycarbonylamino)pentanoylthio>azetidin-2-one

CAS号：105499-99-8

英文名：(3S,4R)-3-<(1R)-(tert-butyldimethylsiloxy)ethyl>-4-<5-(p-nitrobenzyloxycarbonylamino)pentanoylthio>azetidin-2-one

分子式：C24H37N3O7SSi

分子量：539.717

合成路线

(2S,5R,6S)-6-Bromo-6-[1-(tert-butyl-dimethyl-silanyloxy)-ethyl]-3,3-dimethyl-7-oxo-4-thia-1-aza-bicyclo[3.2.0]heptane-2-carboxylic acid methyl ester

(2S,5R,6S)-6-Bromo-6-[1-(tert-butyl-dimethyl-silanyloxy)-ethyl]-3,3-dimethyl-7-oxo-4-thia-1-aza-bicyclo[3.2.0]heptane-2-carboxylic acid methyl ester

(3S,4R)-3-<(1R)-(tert-butyldimethylsiloxy)ethyl>-4-<5-(p-nitrobenzyloxycarbonylamino)pentanoylthio>azetidin-2-one

(3S,4R)-3-<(1R)-(tert-butyldimethylsiloxy)ethyl>-4-<5-(p-nitrobenzyloxycarbonylamino)pentanoylthio>azetidin-2-one

上游原料

(2S,5R,6S)-6-Bromo-6-[1-(tert-butyl-dimethyl-silanyloxy)-ethyl]-3,3-dimethyl-7-oxo-4-thia-1-aza-bicyclo[3.2.0]heptane-2-carboxylic acid methyl ester

下游产品

p-nitrobenzyl 2-<(3S,4R)-3-<(1R)-(tert-butyldimethylsiloxy)ethyl>-4-(5-p-nitrobenzyloxycarbonylaminopentanoylthio)-2-oxoazetidin-1-yl>-2-triphenylphosphoranylideneacetate p-nitrobenzyl (5R,6S)-6-<(1R)-(tert-butyldimethylsiloxy)ethyl>-2-(4-p-nitrobenzyloxycarbonylaminobutan-1-yl)-2-penem-3-carboxylate