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左氧氟环合酯

左氧氟环合酯

CAS号：106939-34-8

英文名：ethyl (S)-(-)-9,10-Difluoro-3-Methyl-7-Oxo-2,3-Dihydro-7H-Pyrido[1,2,3-de]-[1,4]Benzoxazine-6-Carboxylate

分子式

C15H13F2NO4

熔点

258-260ºC

密度

1.43g/cm3

分子量

309.265

沸点

442.2ºC at 760 mmHg

溶解度

信号词

危险品标志

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化合物简介

Levofloxacin intermediate.

基本信息

中文名称

左氧氟环合酯

英文名称

ethyl (S)-(-)-9,10-Difluoro-3-Methyl-7-Oxo-2,3-Dihydro-7H-Pyrido[1,2,3-de]-[1,4]Benzoxazine-6-Carboxylate

中文别名

左氧氟羧酸乙酯、左氧氟沙星环合酯、(S)-9,10-二氟-3-甲基-7-氧代-2,3-二氢-7H-吡啶并[1,2,3-de]-1,4-苯骈恶嗪-6-羧酸乙酯

英文别名

Levofiexacin acid ester、(S)-ethyl-9,10-difluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido-[1,2,3-de]-1,4-benzoxazine-6-carboxylate、(S)-Ethyl 9,10-difluoro-3-methyl-7-oxo-3,7-dihydro-2H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylate、(-)-ethyl 9,10-difluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido<1,2,3-de><1,4>benzoxazine-6-carboxylate、(S)-9,10-Difluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic Acid Ethyl Ester、Levofloxacin cyclized ester、ethyl (S)-(-)-9,10-difluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido[1,2,3-de][1,4]benzoxazine-6-carboxylate

CAS号

106939-34-8

分子式

C15H13F2NO4

分子量

309.265

精确质量

309.081

PSA

57.53

LOGP

2.4098

编号系统

MDL号

MFCD09030626

物化性质

外观与性状

灰白色淡黄色固体

密度

1.43g/cm3

沸点

442.2ºC at 760 mmHg

熔点

258-260ºC

闪点

221.2ºC

折射率

1.582

蒸汽压

5.11E-08mmHg at 25°C

安全信息

海关编码

2934999090

合成路线

共找到1条合成路线 >

(3S)-(+)-7,8-Difluoro-3,4-dihydro-3-methyl-2H-[1,4]benzoxazine

(3S)-(+)-7,8-Difluoro-3,4-dihydro-3-methyl-2H-[1,4]benzoxazine

乙氧基甲叉丙二酸二乙酯

乙氧基甲叉丙二酸二乙酯

左氧氟环合酯

左氧氟环合酯

上游原料

共找到8个上游原料 >

乙氧基甲叉丙二酸二乙酯

乙氧基甲叉丙二酸二乙酯

(-)-ethyl 9,10-difluoro-2,3-dihydro-3-iodomethyl-7-oxo-7H-pyrido[1,2,3-de][1,4]benzoxazine-6-carboxylate

(-)-ethyl 9,10-difluoro-2,3-dihydro-3-iodomethyl-7-oxo-7H-pyrido[1,2,3-de][1,4]benzoxazine-6-carboxylate

(-)-ethyl 9,10-difluoro-2,3-dihydro-3-hydroxymethyl-7-oxo-7H-pyrido<1,2,3-de><1,4>benzoxazine-6-carboxylate

(-)-ethyl 9,10-difluoro-2,3-dihydro-3-hydroxymethyl-7-oxo-7H-pyrido<1,2,3-de><1,4>benzoxazine-6-carboxylate

(+)-ethyl 2-[[[(S)-1-hydroxyprop-2-yl]amino]methylene]-3-oxo-3-(2,3,4,5-tetrafluorophenyl)propionate

(+)-ethyl 2-[[[(S)-1-hydroxyprop-2-yl]amino]methylene]-3-oxo-3-(2,3,4,5-tetrafluorophenyl)propionate

ethyl 9,10-difluoro-3-(hydroxymethyl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylate

ethyl 9,10-difluoro-3-(hydroxymethyl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylate

(S)-ethyl 3-(((3,5-dinitrobenzoyl)oxy)methyl)-9,10-difluoro-7-oxo-3,7-dihydro-2H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylate

(S)-ethyl 3-(((3,5-dinitrobenzoyl)oxy)methyl)-9,10-difluoro-7-oxo-3,7-dihydro-2H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylate

下游产品

共找到1个下游商品 >

左旋氧氟沙星羧酸

左旋氧氟沙星羧酸

上游原料

乙氧基甲叉丙二酸二乙酯 (-)-ethyl 9,10-difluoro-2,3-dihydro-3-iodomethyl-7-oxo-7H-pyrido[1,2,3-de][1,4]benzoxazine-6-carboxylate (-)-ethyl 9,10-difluoro-2,3-dihydro-3-hydroxymethyl-7-oxo-7H-pyrido<1,2,3-de><1,4>benzoxazine-6-carboxylate (+)-ethyl 2-[[[(S)-1-hydroxyprop-2-yl]amino]methylene]-3-oxo-3-(2,3,4,5-tetrafluorophenyl)propionate (S)-ethyl 3-(((3,5-dinitrobenzoyl)oxy)methyl)-9,10-difluoro-7-oxo-3,7-dihydro-2H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylate (3S)-(+)-7,8-Difluoro-3,4-dihydro-3-methyl-2H-[1,4]benzoxazine (+/-)-ethyl 9,10-difluoro-2,3-dihydro-3-(3,5-dinitrobenzoyloxy)methyl-7-oxo-7H-pyrido<1,2,3-de><1,4>benzoxazine-6-carboxylate

下游产品

左旋氧氟沙星羧酸