N-去甲基-4-羟基_CAS号:110025-28-0_分子式、生产方法、用途、产品-灵元素

化合物简介

A novel active metabolite of the anti-cancer drug Tamoxifen. It showed potent ER binding property, blocked estrogen stimulated growth of breast cancer cell and half maximal inhibition of estrogen responsive gene expression in ER pos. human breast cancer cell line.

基本信息

中文名称

N-去甲基-4-羟基

英文名称

4-[1-[4-[2-(methylamino)ethoxy]phenyl]-2-phenylbut-1-enyl]phenol

中文别名

(Z)-4-(1-(4-(2-(甲氨基)乙氧基)苯基)-2-苯基丁-1-烯基)苯酚

英文别名

Phenol,4-[(1E)-1-[4-[2-(methylamino)ethoxy]phenyl]-2-phenyl-1-butenyl]、N-Desmethyl-4-hydroxy Tamoxifen、Phenol,4-[1-[4-[2-(methylamino)ethoxy]phenyl]-2-phenyl-1-buten-1-yl]、E/Z-1-(4-hydroxyphenyl)-1-[4-(2-methylaminoethoxy)phenyl]-2-phenylbutene、E/Z-desmethylhydroxytamoxifen、(E/Z)-desmethyl-4-hydroxytamoxifen、4-[1-[4-[2-(METHYLAMINO)ETHOXY]PHENYL]-2-PHENYL-1-BUTENYL]PHENOL、4-hydroxy-N-desmethyltamoxifen、(E/Z)-Endoxifen

CAS号

110025-28-0

分子式

C25H27NO2

分子量

373.487

精确质量

373.204

PSA

41.49

LOGP

5.7504