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7-乙基-10-羟基喜树碱中间体
CAS号：110351-94-5
英文名：(S)-4-Ethyl-4-hydroxy-7,8-dihydro-1H-pyrano[3,4-f]indolizine-3,6,10(4H)-trione
分子式：C13H13NO5
分子量：263.246
上游原料
(S)-4'-ethyl-4'-(methoxymethoxy)-7',8'-dihydrospiro[[1,3]dioxolane-2,6'-pyrano[3,4-f]indolizine]-3',10'(1'H,4'H)-dione
6-chloro-4-(2-ethyl-1,3-dioxolan-2-yl)-2-methoxypyridine
propyl 5-((benzyloxy)methyl)-4-(2-ethyl-1,3-dioxolan-2-yl)-6-methoxypicolinate
4-ethyl-3-hydroxy-3,4,7,8-tetrahydro-1H,10H-spiro[pyrano[3,4-f]indolizine-6,2'-[1,3]dioxolan]-10-one
1-(2,6-Dichloro-pyridin-4-yl)-propan-1-one
3-((benzyloxy)methyl)-6-chloro-4-(2-ethyl-1,3-dioxolan-2-yl)-2-methoxypyridine
[6-chloro-4-(2-ethyl-1,3-dioxolan-2-yl)-2-methoxypyridin-3-yl]methanol
4'-ethyl-1',4',7',8'-tetrahydro-4'-hydroxy-3'H,10'H-spiro[1,3-dioxolane-2,6'-pyrano[3,4-f]indolizine]-3',10'-dione
6-Chloro-4-(2-ethyl-[1,3]dioxolan-2-yl)-2-methoxy-pyridine-3-carbaldehyde
柠嗪酸
propyl (4S)-4-ethyl-3,4-dihydroxy-8-methoxy-1,3-dihydropyrano[3,4-c]pyridine-6-carboxylate
(S)-α-ethyl-α-hydroxy-1,1-(ethylenedioxy)-6-hydroxymethyl-5-oxo-1,2,3,5-tetrahydroindolizine-7-[N-(1S)-1-phenylethyl]acetamide
2,6-二氯异烟酸
ethyl (S)-2-[N-tosyl-(R)-prolyloxy]-2-[6-(acetoxymethyl)-1,1-(ethylenedioxy)-5-oxo-1,2,3,5-tetrahydroindolizin-7-yl]butanoate
propyl 5-((benzyloxy)methyl)-4-(but-1-en-2-yl)-6-methoxypicolinate
ethyl 2-[N-tosyl-(R)-prolyloxy]-2-[6-cyano-1,1-(ethylenedioxy)-5-oxo-1,2,3,5-tetrahydroindolizin-7-yl]acetate
ethyl bromo-[6-cyano-1,1-(ethylenedioxy)-5-oxo-1,2,3,5-tetrahydroindolizin-7-yl] acetate
propyl 4-(1,2-dihydroxybutan-2-yl)-6-methoxy-5-(phenylmethoxymethyl)pyridine-2-carboxylate
tert-butyl (4S)-4-ethyl-4,6-dihydroxy-3,10-dioxo-1,8-dihydropyrano[3,4-f]indolizine-7-carboxylate
(4'S)-4'-ethyl-1',4',7',8'-tetrahydro-4'-hydroxy-3'H,10'H-spiro[1,3-dioxolane-2,6'-pyrano[3,4-f]indolizine]-3',10'-dione
propyl (S)-4-ethyl-3,4-dihydro-4-hydroxy-8-methoxy-3-oxo-1H-pyrano[3,4-c]pyridine-6-carboxylate
1,1-ethylenedioxy-5-oxo-(5'-ethyl-2'H,5'H,6'H-6-oxopyran)-[3',4',f]-Δ6(8)-tetrahydroindolizine
propyl (S)-4-ethyl-3,4,7,8-tetrahydro-4-hydroxy-3,8-dioxo-1H-pyrano[3,4-c] pyridine-6-carboxylate
4-acetoxy-4-ethyl-6,6-(ethylenedioxy)-7,8-dihydro-1H-pyrano[3,4-f]indolizine-3,10(4H)-dione
6-cyano-1,1-(ethylenedioxy)-7-[(ethoxycarbonyl)methyl]-5-oxo-Δ6(8)-tetrahydroindolizine
ethyl (S)-2-[N-tosyl-(R)-prolyloxy]-2-[6-cyano-1,1-(ethylenedioxy)-5-oxo-1,2,3,5-tetrahydroindolizin-7-yl]butanoate
ethyl (S)-2-[N-tosyl-(R)-prolyloxy]-2-[6-(acetylaminomethyl)-1,1-(ethylenedioxy)-5-oxo-1,2,3,5-tetrahydroindolizin-7-yl]butanoate
(S)-α-Ethyl-1,1-(ethylenedioxy)-α-hydroxy-6-(hydroxymethyl)-N-[(R)-1-phenylethyl]-5-oxo-1,2,3,5-tetrahydroindolizine-7-acetamide
5-Benzyloxymethyl-4-((S)-1-formyl-1-hydroxy-propyl)-6-methoxy-pyridine-2-carboxylic acid propyl ester
