化合物简介
Efonidipine (INN) is a dihydropyridine calcium channel blocker marketed by Shionogi & Co. of Japan. It was launched in 1995, under the brand name Landel (ランデル). The drug blocks both T-type and L-type calcium channels.
基本信息
中文名称
依福地平
英文名称
2-(N-benzylanilino)ethyl 5-(5,5-dimethyl-2-oxo-1,3,2λ<sup>5</sup>-dioxaphosphinan-2-yl)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3-carboxylate
中文别名
英文别名
3-(benzyl-(phenyl)amino)ethyl-5-(5,5-dimethyl-2-oxo-1,3-dioxaphosphorinane-2-yl)-1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-pyridine、Efonidipine [INN]、2-[benzyl(phenyl)amino]ethyl 5-(5,5-dimethyl-2-oxo-1,3,2-dioxaphosphorinan-2-yl)-1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3-pyridinecarboxylate、Efonidipine、Efonidipine HCl
CAS号
111011-63-3
分子式
C34H38N3O7P
分子量
631.655
精确质量
631.245
PSA
132.73
LOGP
8.1552
物化性质
密度
1.3g/cm3
沸点
746.9ºC at 760mmHg
闪点
405.5ºC