化合物简介
ICI-199,441 is a drug which acts as a potent and selective κ-opioid agonist, and has analgesic effects. It is a biased agonist of the KOR, and is one of a relatively few KOR ligands that is G protein-biased rather than β-arrestin-biased.
基本信息
中文名称
ICI-199,441盐酸盐
英文名称
ICI 199,441 hydrochloride,2-(3,4-Dichlorophenyl)-N-methyl-N-[(1S)-1-phenyl-2-(1-pyrrolidinyl)ethyl]acetamidehydrochloride
中文别名
英文别名
ICI 199,441、ICI 199,441 HYDROCHLORIDE
CAS号
115199-84-3
分子式
C21H25Cl3N2O
分子量
427.795
精确质量
426.103
PSA
23.55
LOGP
5.5713
物化性质
沸点
532.8ºC at 760mmHg
闪点
276ºC
蒸汽压
1.97E-11mmHg at 25°C
