化合物简介
20β-Dihydrocortisol could be used as a potential non invasive diagnostic test of transmissible spongiform encephalopaties. 20β-Dihydrocortisol is a metabolite of Cortisol, a steroid hormone, more specifically a glucocorticoid, produced by the zona fasciculata of the adrenal gland. Cortisol is released in response to stress and a low level of blood glucocorticoids. Its primary functions are to increase blood sugar through gluconeogenesis; suppress the immune system; and aid in fat, protein and carbohydrate metabolism.
基本信息
中文名称
(11beta,20S)-11,17,20,21-四羟基孕甾-4-烯-3-酮
英文名称
(8S,9S,10R,11S,13S,14S,17R)-17-[(1R)-1,2-dihydroxyethyl]-11,17-dihydroxy-10,13-dimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one
中文别名
英文别名
20beta-Dihydrocortisol、Reichstein\'s substance E、4-Pregnene-11beta,17alpha,20beta,21-tetrol-3-one、UNII-77U6C4OLOR、20beta-Hydroxycortisol、delta4-Pregnene-11beta,17alpha,20beta,21-tetraol-3-one、Reichstein\'s compound E、Pregn-4-en-3-one, 11,17,20,21-tetrahydroxy-, (11β,20R)-
CAS号
116-58-5
分子式
C21H32O5
分子量
364.476
精确质量
364.225
PSA
97.99
LOGP
1.5734
物化性质
密度
1.29g/cm3
沸点
586.6ºC at 760 mmHg
闪点
322.6ºC
折射率
1.602
蒸汽压
3.34E-16mmHg at 25°C
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