5-羟基地氯雷他定

5-羟基地氯雷他定

CAS号：117811-12-8

英文名：8-chloro-11-piperidin-4-ylidene-5,6-dihydrobenzo[1,2]cyclohepta[2,4-b]pyridin-5-ol

分子式

C19H19ClN2O

熔点

密度

分子量

326.82

沸点

溶解度

信号词

危险品标志

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化合物简介

A hydroxylated metabolite of Desloratadine.

基本信息

中文名称

5-羟基地氯雷他定

英文名称

8-chloro-11-piperidin-4-ylidene-5,6-dihydrobenzo[1,2]cyclohepta[2,4-b]pyridin-5-ol

中文别名

英文别名

5-OH desloratadine、5-Hydroxydesloratadine

CAS号

117811-12-8

分子式

C19H19ClN2O

分子量

326.82

精确质量

326.119

PSA

45.15

LOGP

3.8386

合成路线

8-Chloro-6,11-dihydro-11-(4-piperidinylidene)-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-5-one

8-Chloro-6,11-dihydro-11-(4-piperidinylidene)-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-5-one

5-羟基地氯雷他定

5-羟基地氯雷他定

上游原料

共找到10个上游原料 >

2,2,2-Trichloroethyl 4-(8-Chloro-5,6-dihydro-5-hydroxy-11H-benzo<5,6>cyclohepta<1,2-b>pyridin-11-ylidene)-1-piperidinecarboxylate

2,2,2-Trichloroethyl 4-(8-Chloro-5,6-dihydro-5-hydroxy-11H-benzo<5,6>cyclohepta<1,2-b>pyridin-11-ylidene)-1-piperidinecarboxylate

8-Chloro-6,11-dihydro-11-(1-methyl-4-piperidinylidene)-5H-benzo<5,6>cyclohepta<1,2-b>pyridin-5-one

8-Chloro-6,11-dihydro-11-(1-methyl-4-piperidinylidene)-5H-benzo<5,6>cyclohepta<1,2-b>pyridin-5-one

2,2,2-Trichloroethyl 4-<8-Chloro-5-<<<(2,2,2-trichloroethyl)oxy>carbonyl>oxy>-11H-benzo<5,6>cyclohepta<1,2-b>pyridin-11-ylidene>-1-piperidinecarboxylate

2,2,2-Trichloroethyl 4-<8-Chloro-5-<<<(2,2,2-trichloroethyl)oxy>carbonyl>oxy>-11H-benzo<5,6>cyclohepta<1,2-b>pyridin-11-ylidene>-1-piperidinecarboxylate

8-氯-5,6-二氢-11H-苯并[5,6]环庚烷并[1,2-b]吡啶-11-酮

8-氯-5,6-二氢-11H-苯并[5,6]环庚烷并[1,2-b]吡啶-11-酮

8-Chloro-6,11-dihydro-11-(4-piperidinylidene)-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-5-one

8-Chloro-6,11-dihydro-11-(4-piperidinylidene)-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-5-one

8-chloro-11H-benzo[5,6]-cyclohepta[1,2-b]pyridin-11-one

8-chloro-11H-benzo[5,6]-cyclohepta[1,2-b]pyridin-11-one

上游原料

2,2,2-Trichloroethyl 4-(8-Chloro-5,6-dihydro-5-hydroxy-11H-benzo<5,6>cyclohepta<1,2-b>pyridin-11-ylidene)-1-piperidinecarboxylate 8-Chloro-6,11-dihydro-11-(1-methyl-4-piperidinylidene)-5H-benzo<5,6>cyclohepta<1,2-b>pyridin-5-one 2,2,2-Trichloroethyl 4-<8-Chloro-5-<<<(2,2,2-trichloroethyl)oxy>carbonyl>oxy>-11H-benzo<5,6>cyclohepta<1,2-b>pyridin-11-ylidene>-1-piperidinecarboxylate 8-氯-5,6-二氢-11H-苯并[5,6]环庚烷并[1,2-b]吡啶-11-酮 8-Chloro-6,11-dihydro-11-(4-piperidinylidene)-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-5-one 8-chloro-11H-benzo[5,6]-cyclohepta[1,2-b]pyridin-11-one 5-Methoxy-8-chloro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-one 5-Methoxy-8-chloro-11-(1-methyl-4-piperidinyl)-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ol Ethyl 4-[8-Chloro-5-[(ethoxycarbonyl)oxy]-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene]-1-piperidinecarboxlate 8-Chloro-6,11-dihydro-11-(1-methyl-4-piperidinyl)-5,11-epoxy-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-5-ol