化合物简介
Melanotan II (i) is a synthetic analogue of the naturally-occurring melanocortin peptide hormone α-melanocyte-stimulating hormone (α-MSH) that in usage has been shown to produce melanogenesis (part of the tanning process that produces darkening pigmentation in the skin) and have aphrodisiac effects in preliminary studies and clinical trials. Developed at the University of Arizona, it is a cyclic lactam analogue of α-MSH with the amino acid sequence Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-NH2.
基本信息
中文名称
美拉诺坦 II
英文名称
Melanotan II acetate salt
中文别名
醋酸美拉诺坦Ⅱ MELANOTANⅡACETATE、醋酸美拉诺坦Ⅱ MELANOTANII ACETATE(MT-2)、醋酸美拉诺坦II、Ac-[Nle4Asp5D-Phe7Lys10]α-MSH-(4-10)-NH2、美拉诺坦2、醋酸美拉诺坦醋酸
英文别名
(3S,6S,9R,12S,15S,23S)-15-[[(2S)-2-acetamidohexanoyl]amino]-9-benzyl-6-[3-(diaminomethylideneamino)propyl]-12-(1H-imidazol-5-ylmethyl)-3-(1H-indol-3-ylmethyl)-2,5,8,11,14,17-hexaoxo-1,4,7,10,13,18-hexazacyclotricosane-23-carboxamide
CAS号
121062-08-6
分子式
C50H69N15O9
分子量
1024.18
精确质量
1023.54
PSA
382.26
LOGP
3.6072
物化性质
外观与性状
固体
密度
1.43 g/cm3
折射率
1.669
储存条件
-20ºC
安全信息
WGK Germany
3
