百科

那拉曲坦

CAS号：121679-13-8

英文名：naratriptan

分子式

C17H25N3O2S

熔点

密度

1.227g/cm3

分子量

335.464

沸点

541.3ºC at 760 mmHg

溶解度

信号词

危险品标志

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化合物简介

Naratriptan (trade names include Amerge and Naramig) is a triptan drug marketed by GlaxoSmithKline and is used for the treatment of migraine headaches. Naratriptan is available in 2.5mg tablets. It is a selective 5-HT1 receptor subtype agonist.

基本信息

中文名称

那拉曲坦

英文名称

naratriptan

中文别名

英文别名

Naramig、Amerge、UNII-QX3KXL1ZA2、N-methyl-2-[3-(1-methylpiperidin-4-yl)-1H-indol-5-yl]ethanesulfonamide、Colatan

CAS号

121679-13-8

分子式

C17H25N3O2S

分子量

335.464

精确质量

335.167

PSA

73.58

LOGP

3.4784

编号系统

UNII

QX3KXL1ZA2

物化性质

密度

1.227g/cm3

沸点

541.3ºC at 760 mmHg

闪点

281.2ºC

折射率

1.605

蒸汽压

8.81E-12mmHg at 25°C

安全信息

海关编码

2935009090

合成路线

共找到1条合成路线 >

121679-20-7

N-甲基-3-(1,2,3,6-四氢-1-甲基-4-吡啶)-1H-吲哚-5-乙烷磺酰胺

上游原料

2-hydroxy-2-(4-nitrophenyl)ethanesulfonic acid isopropyl ester

N-{4-[2-(benzylmethylsulfamoyl)ethyl]phenyl}-N-(2,2-dimethoxyethyl)-2,2,2-trifluoroacetamide

894351-84-9

(E)-2-(1-苄基-1H-吲哚-5-基)-N-甲基乙烯磺酰胺

1268265-90-2

N-[2-iodo-4-[2-(methylsulfamoyl)ethyl]phenyl]acetamide

下游产品

共找到1个下游商品 >

143388-64-1

盐酸那拉曲普坦

上游原料

2-hydroxy-2-(4-nitrophenyl)ethanesulfonic acid isopropyl ester 对硝基苯甲醛 1-苄基-1H-吲哚-5-甲醛 N-{4-[2-(benzylmethylsulfamoyl)ethyl]phenyl}-N-(2,2-dimethoxyethyl)-2,2,2-trifluoroacetamide (E)-2-(1-苄基-1H-吲哚-5-基)-N-甲基乙烯磺酰胺 N-[2-iodo-4-[2-(methylsulfamoyl)ethyl]phenyl]acetamide 2-[1-苄基-3-(1-甲基-1,2,3,6-四氢-4-吡啶基)-1H-吲哚-5-基]-N-甲基乙烷磺酰胺 2-(1-苄基-1H-吲哚-5-基)乙烷磺酸甲酰胺 N-甲基-4-哌啶酮 trans-2-(p-nitrophenyl)ethenesulfonyl chloride N-甲基-1H-吲哚-5-乙基磺酰胺 2-[4-(2,2-dimethoxyethylamino)phenyl]ethanesulfonic acid benzylmethylamide 4-氨基-N-甲基苯乙基磺酰胺 2-(4-nitrophenyl)ethenesulfonic acid benzylmethylamide 2-(4-amino-3-iodo-phenyl)ethanesulfonic acid methylamide N-methyl-N-phenylmethyl-2-(4-aminophenyl)-ethanesulfonamide 2-(4-benzylamino-3-ethynylphenyl)ethanesulfonic acid methylamide N-甲基-3-(1,2,3,6-四氢-1-甲基-4-吡啶)-1H-吲哚-5-乙烷磺酰胺 N-[2-ethynyl-4-(2-(methylsulfamoyl)ethyl)phenyl]acetamide 2-(4-benzylamino-3-iodophenyl)ethanesulfonic acid methylamide 2-[1-(2,2,2-trifluoroacetyl)-1H-indol-5-yl]ethanesulfonic acid benzylmethylamide N-[4-(2-{methylsulfamoyl}ethyl)-2-{2-(trimethylsilanyl)ethynyl}phenyl]acetamide 2-(1H-indol-5-yl)ethanesulfonic acid benzylmethylamide 2-[3-(1-methyl-1,2,3,6-tetrahydropyridin-4-yl)-1H-indol-5-yl]ethanesulfonic acid benzylmethylamide N-benzylindoline-5-carboxaldehyde 2-(4-benzylamino-3-trimethylsilanylethynyl-phenyl)ethanesulfonic acid methylamide 2-[3-(1-methylpiperidin-4-yl)-1H-indol-5-yl]ethanesulfonic acid benzylmethylamide 2-hydroxy-2-(4-nitrophenyl)ethanesulfonic acid benzylmethylamide

下游产品

盐酸那拉曲普坦