化合物简介
3-(2-Amino-5-benzoxazolyl)-1-(1-methylethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine is a potent and selective TORC1/2 inhibitor with broad oral antitumor activity. TORC1/2 inhibitors are mechanistically distinct from rapamycinand offer a compelling approach to the treatment of cancer by targeting translational control, cell metabolism, growth andangiogenesis.
基本信息
中文名称
INK 128
英文名称
5-(4-amino-1-propan-2-ylpyrazolo[3,4-d]pyrimidin-3-yl)-1,3-benzoxazol-2-amine
中文别名
3-(2-氨基-5-苯并恶唑基)-1-(1-甲基乙基)-1H-吡唑并[3,4-D]嘧啶-4-胺
英文别名
INK-128/INK128、CS-0557、INK 128
CAS号
1224844-38-5
分子式
C15H15N7O
分子量
309.326
精确质量
309.134
PSA
121.67
LOGP
3.5422
编号系统
UNII
JGH0DF1U03
