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D-鞘氨醇

D-鞘氨醇

CAS号：123-78-4

英文名：sphingosine

分子式

C18H37NO2

熔点

81-82ºC

密度

0.939g/cm3

分子量

299.492

沸点

445.9ºC at 760mmHg

溶解度

信号词

危险品标志

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化合物简介

鞘氨醇（Sphingosine）又称神经鞘胺醇，学名2-氨基-4-十八烯-1,3-二醇，是一种含有不饱和烃基链的十八碳氨基醇。鞘氨醇属于鞘脂类，为细胞膜组成成分之一。

基本信息

中文名称

D-鞘氨醇

英文名称

sphingosine

中文别名

D-赤型神经胺、(2S,3R,E)-2-氨基-4-十八烯-1,3-二醇

英文别名

[3H]-Sphingosine、D-Sphingosine、SPHINGOSINE、(2S,3R,4E)-2-amino-3-hydroxyoctadec-4-ene-1-ol、[Fluorescein]-Sphingosine、4-SPHINGENINE、BRAIN,BOVINE、C18-Sphingosine、BRAIN SPHINGOSINE、D-SPHINGOSINE、(2S,3R,E)-2-Amino-4-octadecene-1,3-diol、D-erythro-Sphingosine、Sphingenine、(-)-D-erythro-Sphingosine、D-erythro-Sphingosine,synthetical、D-ERYTHRO-SPHINGOSINE、CEREBROSIDE、EGG SPHINGOSINE、Sphingosine 2S,3R,2S,3R,4E)-2-aminooctadec-4-ene-1,3-diol

CAS号

123-78-4

分子式

C18H37NO2

分子量

299.492

精确质量

299.282

PSA

66.48

LOGP

4.6245

编号系统

MDL号

MFCD00036751

EINECS号

204-651-3

BRN号

1727294

物化性质

外观与性状

白色至灰白色结晶粉末

密度

0.939g/cm3

沸点

445.9ºC at 760mmHg

熔点

81-82ºC

折射率

1.489

稳定性

Stable. Incompatible with strong acids, strong bases, strong oxidizing agents.

储存条件

-20ºC

蒸汽压

7.96E-10mmHg at 25°C

安全信息

安全说明

S22

海关编码

2922199090

生产方法及用途

用途

生化研究

合成路线

共找到24条合成路线 >

N-叔丁氧羰基-赤式-鞘氨醇

N-叔丁氧羰基-赤式-鞘氨醇

D-鞘氨醇

上游原料

共找到114个上游原料 >

Phenyl 2,3,4-tris-O-(tert-butyldimethylsilyl)-1-thio-β-D-xylopyranoside

Phenyl 2,3,4-tris-O-(tert-butyldimethylsilyl)-1-thio-β-D-xylopyranoside

1,5-Anhydro-3,4-bis-O-(tert-butyldimethylsilyl)-2-deoxy-1-phenylsulfonyl-D-threo-pent-1-enitol

1,5-Anhydro-3,4-bis-O-(tert-butyldimethylsilyl)-2-deoxy-1-phenylsulfonyl-D-threo-pent-1-enitol

(2S,3R,4E)-2-Amino-3-benzyloxymethoxy-1-hydroxy-4-octadecene

(2S,3R,4E)-2-Amino-3-benzyloxymethoxy-1-hydroxy-4-octadecene

(2S,3R)-2-amino-1,3-(dibenzyloxy)-octadeca-4-ene

(2S,3R)-2-amino-1,3-(dibenzyloxy)-octadeca-4-ene

threo-4-(1-hydroxy-2-hexadecenyl)-2-phenyl-Δ2-oxazoline

threo-4-(1-hydroxy-2-hexadecenyl)-2-phenyl-Δ2-oxazoline

2-phenyl-4-(S)-[(1R,2E)-1-(trimethylsilanyl-oxy)hexadec-2-enyl]-1,3-oxazoline

2-phenyl-4-(S)-[(1R,2E)-1-(trimethylsilanyl-oxy)hexadec-2-enyl]-1,3-oxazoline

下游产品

共找到16个下游商品 >

D-苏式-鞘胺醇-1-磷酸

D-苏式-鞘胺醇-1-磷酸

N-辛酰基-D-神经鞘氨醇

N-辛酰基-D-神经鞘氨醇

十三酸

N-月桂酰-D-鞘胺醇

N-月桂酰-D-鞘胺醇

N-油酰基-D-鞘氨醇

N-油酰基-D-鞘氨醇

D-鞘氨醇

上游原料

Phenyl 2,3,4-tris-O-(tert-butyldimethylsilyl)-1-thio-β-D-xylopyranoside 1,5-Anhydro-3,4-bis-O-(tert-butyldimethylsilyl)-2-deoxy-1-phenylsulfonyl-D-threo-pent-1-enitol (2S,3R,4E)-2-Amino-3-benzyloxymethoxy-1-hydroxy-4-octadecene (2S,3R)-2-amino-1,3-(dibenzyloxy)-octadeca-4-ene threo-4-(1-hydroxy-2-hexadecenyl)-2-phenyl-Δ2-oxazoline 2-phenyl-4-(S)-[(1R,2E)-1-(trimethylsilanyl-oxy)hexadec-2-enyl]-1,3-oxazoline ethyl (2R,3R)-2-azido-3-hydroxyoctadec-4-ynoate 2-Benzamido-2-deoxy-4,6-O-ethylidene-D-glucitol (2S,3S,4R)-2-叠氮基-1,3,4-十八烷三醇 (2S,3R,4E)-2-叠氮-4-十八碳烯-1,3-二醇 (2R,4S,5R)-4-((4S,5S)-4-(((tert-butyldiphenylsilyl)oxy)methyl)-2-phenyl-4,5-dihydrooxazol-5-yl)-2-methyl-1,3-dioxan-5-yl methanesulfonate triacetyl-D-erythro-sphingosine (2R,3R,E)-2-amino-1-((S)-2,2-dimethyl-4-(2-(methylthio)ethyl)oxazolidin-3-yl)-3-hydroxyoctadec-4-en-1-one (4R,5S)-2,2-di-tert-butyl-4-((E)-pentadec-1-en-1-yl)-1,3,2-dioxasilinan-5-amine (2S,3R,4E)-2-叔-丁基氧羰基氨基-1-三苯基甲基氧基-4-十八碳烯-2-醇 (2S,4R,5R)-4-((Z)-2-(tert-butyldimethylsilyl)pentadec-1-en-1-yl)-2-phenyl-1,3-dioxan-5-ol (1S,2R)-1-((4S,5S)-4-(((tert-butyldiphenylsilyl)oxy)methyl)-2-phenyl-4,5-dihydrooxazol-5-yl)-1,3-dihydroxypropan-2-yl methanesulfonate (2S,3R)-(4E)-1-(tert-butyldiphenylsilyloxy)-2-phthalimido-octadec-4-en-3-ol (2S,3R,E)-1,3-bis(benzyloxy)octadec-4-en-2-amine (2S,3R)-2-amino-1,3-dihydroxyoctadec-4-yne N-CBZ-sphingosine (4S)-3-((2'R,3'R,4'E)-2'-azido-3'-hydroxy-4'-octadecenoyl)-4-(isopropyl)-2-oxazolidinone octadeca-2,4-dien-1-ol (2R,3R,Z)-5-(tert-butyldimethylsilyl)-2-((tert-butyldimethylsilyl)oxy)octadec-4-ene-1,3-diol 2,3,4-Tris-O-(tert-butyldimethylsilyl)-β-D-xylopyranosyl phenyl sulfone [4S-[4α,5α(E)]]-4-(hydroxymethyl)-5-(1-pentadecenyl)-2-oxazolidinone (2S,3R,4E)-2-叠氮-3-(叔丁基二甲基硅烷)-赤-鞘氨醇 (2S,3S,4S)-2-(tert-butyloxycarbonylamino)octadecane-1,3,4-triol N-乙酰基神经鞘氨醇肉豆蔻醛 N-[(2S,3R,E)-1,3-dihydroxyoctadec-4-en-2-yl]-2,2,2-trifluoroacetamide tert-butyl (4S)-4-[(1R,2E)-1-hydroxy-2-hexadecenyl]-2,2-dimethyl-1,3-oxazolidine-3-carboxylate (2R,3R)-trans-2-azide-1,3-O-benzylidene-1,3-octadec-4-enediol ethyl (2E,4E)-octadeca-2,4-dienoate (2S,3R,E)-2-amino-3-(benzyloxy)octadec-4-en-1-ol (2E,3E)-octadeca-2,4-dienyloxymethylbenzene (2S,3R,4E)-2-amino-1-benzyloxyoctadec-4-en-3-ol trans-2-hexadecenal (4S,1'R)-4-(1'-Hydroxy-2'-hexadecinyl)-2,2-dimethyl-3-oxazolidincarbonsaeure-tert-butylester (2S,4R,5R)-4-[(1E)-1-十五碳烯-1-基]-2-苯基-1,3-二恶烷-5-醇糖脂 {(2S,3S)-3-[(4S,5S)-4-(tert-Butyl-diphenyl-silanyloxymethyl)-2-phenyl-4,5-dihydro-oxazol-5-yl]-oxiranyl}-methanol (2'E,4S,1'R)-4-(1'-hydroxyhexadec-2'-enyl)-1,3-oxazolidin-2-one N-叔丁氧羰基-赤式-鞘氨醇正十四烷基三苯基溴化膦 (S)-4-((R,E)-1-(methoxymethoxy)hexadec-2-en-1-yl)-3-(methoxymethyl)oxazolidin-2-one (((3R,4R)-6-(phenylsulfinyl)-3,4-dihydro-2H-pyran-3,4-diyl)bis(oxy))bis(tert-butyldimethylsilane) (4S)-3-((2'S,3'R,4'E)-2'-bromo-3'-hydroxy-4-(isopropyl)-4'-octadecenoyl)-2-oxazolidinone (4S)-3-((2'R,3'R,4'E)-2'-azido-3-O-tert-butyldimethylsilyl-3'-hydroxy-4'-octadecenoyl)-4-(isopropyl)-2-oxazolidinone

下游产品

D-苏式-鞘胺醇-1-磷酸 N-辛酰基-D-神经鞘氨醇十三酸 N-月桂酰-D-鞘胺醇 N-油酰基-D-鞘氨醇 D-鞘氨醇神经酸酰胺 N-叔丁氧羰基-赤式-鞘氨醇肉豆蔻酸 1-hydroxyoctadecan-3-one N-乙酰基神经鞘氨醇十六碳酰胺 (2S,3R,4E)-2-叠氮-4-十八碳烯-1,3-二醇 N-(1,3-dihydroxyoctadec-4-en-2-yl)octadecanamide D-赤式-二氢-D-鞘氨醇 N-乙酰基二氢鞘氨醇