化合物简介
Zatosetron (LY-277,359) is a drug which acts as an antagonist at the 5HT3 receptor It is orally active and has a long duration of action, producing antinauseant effects but without stimulating the rate of gastrointestinal transport. It is also an effective anxiolytic in both animal studies and human trials, although with some side effects at higher doses.
基本信息
中文名称
扎托司琼
英文名称
5-chloro-2,2-dimethyl-N-(8-methyl-8-azabicyclo[3.2.1]octan-3-yl)-3H-1-benzofuran-7-carboxamide
中文别名
英文别名
Zatosetronum、Zatosetronum [INN-Latin]、ZATOSETRON、Zatosetron [INN:BAN]、7-Benzofurancarboxamide,5-chloro-2,3-dihydro-2,2-dimethyl-N-(8-methyl-8-azabicyclo(3.2.1)oct-3-yl)-,endo、UNII-901MC95XSB
CAS号
123482-22-4
分子式
C19H25ClN2O2
分子量
348.867
精确质量
348.16
PSA
41.57
LOGP
3.7373
编号系统
UNII
901MC95XSB
物化性质
密度
1.26g/cm3
沸点
435.1ºC at 760mmHg
闪点
216.9ºC
折射率
1.604
蒸汽压
8.99E-08mmHg at 25°C
上游原料
共找到7个上游原料 >