化合物简介
Gestonorone caproate (INN, USAN, JAN) (brand names Depostat, Primostat), also known as gestronol (BAN) (free alcohol) and gestronol hexanoate (BANM), as well as 17α-hydroxy-19-norprogesterone caproate, is a synthetic, steroidal progestin. As a depot administered via intramuscular injection, it is used in the treatment of benign prostatic hypertrophy (BPH) and endometrial cancer. It has been marketed since at least 1973.
基本信息
中文名称
己酸各司孕甾醇
英文名称
GESTONORONE CAPROATE
中文别名
己酸孕诺酮
英文别名
17-Hexanoyloxy-19-nor-pregn-4-en-3,20-dion、Depostat、Depostat (TN)、Gestronol caproate、Primostat、ZK 5623、17-hexanoyloxy-19-nor-pregn-4-ene-3,20-dione、Gestronol hexanoate、SH 582
CAS号
1253-28-7
分子式
C26H38O4
分子量
414.578
精确质量
414.277
PSA
60.44
LOGP
5.5795
编号系统
UNII
U38E620NS6
物化性质
密度
1.11g/cm3
沸点
535.4ºC at 760mmHg
闪点
228.4ºC
折射率
1.534
蒸汽压
1.54E-11mmHg at 25°C