化合物简介
Seproxetine, also known as (S)-norfluoxetine, is a selective serotonin reuptake inhibitor (SSRI). It is the most important active metabolite of the widely used antidepressant fluoxetine, but little is known about its pharmacological actions. Seproxetine was being investigated by Eli Lilly and Company as an antidepressant; however, a cardiac side effect was noted and development was discontinued.
基本信息
中文名称
(3S)-3-苯基-3-[4-(三氟甲基)苯氧基]-1-丙胺
英文名称
(3S)-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine
中文别名
英文别名
UNII-25CO3X0R31、SEPROXETINE
CAS号
126924-38-7
分子式
C16H16F3NO
分子量
295.3
精确质量
295.118
PSA
35.25
LOGP
4.8746
物化性质
密度
1.204g/cm3
沸点
381.1ºC at 760 mmHg
闪点
184.3ºC
折射率
1.525
蒸汽压
5.21E-06mmHg at 25°C
安全信息
海关编码
2922299090
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