化合物简介
Satraplatin (INN, codenamed JM216) is a platinum-based antineoplastic agent that is under investigation as one treatment of patients with advanced prostate cancer who have failed previous chemotherapy. It has not yet received approval from the U.S. Food and Drug Administration. First mentioned in the medical literature in 1993, satraplatin is the first orally active platinum-based chemotherapeutic drug; other available platinum analogues—cisplatin, carboplatin, and oxaliplatin—must be given intravenously.
基本信息
中文名称
顺式-二氯-反式-二乙酸-氨-环己胺合铂
英文名称
satraplatin
中文别名
塞特铂
英文别名
YHI-601、acetic acid,azane,cyclohexanamine,dichloroplatinum、JM-216
CAS号
129580-63-8
分子式
C10H22Cl2N2O4Pt
分子量
500.277
精确质量
499.06
PSA
81.86
LOGP
3.7061
物化性质
沸点
134.5ºCat 760 mmHg
闪点
32.2ºC
蒸汽压
8.07mmHg at 25°C
合成路线