化合物简介
Nifekalant (INN) is a class III antiarrhythmic agent approved in Japan for the treatment of arrhythmias and ventricular tachycardia. It has the brand name Shinbit.
基本信息
中文名称
尼非卡兰
英文名称
Nifekalant
中文别名
6-[[N-(2-羟乙基)-N-(4-硝基苯基丙基)氨基]乙基氨基]-1,3-二甲基-2,4-嘧啶二酮
英文别名
6-[2-[2-hydroxyethyl-[3-(4-nitrophenyl)propyl]amino]ethylamino]-1,3-dimethyl-pyrimidine-2,4-dione、1,3-dimethyl-6-<<2-<N-<3-(4-nitrophenyl)-propyl>-N-(hydroxyethyl)amino>ethyl>amino>-2,4(1H,3H)-pyrimidinedione、1,3-dimethyl-6-{2-{N-(2-hydroxyethyl)-N-[3-(4-nitrophenyl) propyl]amino}ethylamino}-2,4-(1H,3H)-pyrimidinedione、6-((2-((2-hydroxyethyl)(3-(p-nitrophenyl)propyl)amino)ethyl)amino)-1,3-dimethyl-uracil、1,3-dimethyl-6-[2-(n-(2-hydroxyethyl)-3-(4-nitrophenyl)propylamino)ethylamino]-2,4(1h,3h)-pyrimidinedione hydrochloride、6-[2-[2-hydroxyethyl-[3-(4-nitrophenyl)propyl]amino]ethylamino]-1,3-dimethyl-pyrimidine-2,4-quinone、NIFEKALANT HCL、1,3-dimethyl-6-{2-[N-(2-hydroxyethyl)-3-(4-nitrophenyl)propylamino]ethylamino}-2,4(1H,3H)-pyrimidinedione、NIFEKALANT [6-((2-((2-HYDROXYETHYL)(3-(P-NITROPHENYL)PROPYL)AMINO)ETHYL)AMINO)-1,3-DIMETHYL-URACIL]
CAS号
130636-43-0
分子式
C19H28ClN5O5
分子量
441.909
精确质量
441.178
PSA
125.32
LOGP
1.7294
物化性质
外观与性状
晶体
密度
1.32 g/cm3
沸点
597.9ºC at 760 mmHg
熔点
117.5-118.5ºC
闪点
315.4ºC
蒸汽压
3.84E-15mmHg at 25°C
