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(E)-(1R,9S,12R,18S,19S,20S,21S,23R)-1-Hydroxy-12-[(E)-2-((1R,3R,4R)-4-hydroxy-3-methoxy-cyclohexyl)-1-methyl-vinyl]-18-isopropyl-19,21-dimethoxy-13,13,23-trimethyl-11,17,24-trioxa-4-aza-tricyclo[18.3.1.04,9]tetracos-14-ene-2,3,10,16-tetraone

(E)-(1R,9S,12R,18S,19S,20S,21S,23R)-1-Hydroxy-12-[(E)-2-((1R,3R,4R)-4-hydroxy-3-methoxy-cyclohexyl)-1-methyl-vinyl]-18-isopropyl-19,21-dimethoxy-13,13,23-trimethyl-11,17,24-trioxa-4-aza-tricyclo[18.3.1.04,9]tetracos-14-ene-2,3,10,16-tetraone

CAS号：131190-66-4

英文名：(E)-(1R,9S,12R,18S,19S,20S,21S,23R)-1-Hydroxy-12-[(E)-2-((1R,3R,4R)-4-hydroxy-3-methoxy-cyclohexyl)-1-methyl-vinyl]-18-isopropyl-19,21-dimethoxy-13,13,23-trimethyl-11,17,24-trioxa-4-aza-tricyclo[18.3.1.04,9]tetracos-14-ene-2,3,10,16-tetraone

分子式

C38H59NO12

熔点

密度

分子量

721.875

沸点

溶解度

信号词

危险品标志

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基本信息

中文名称

(E)-(1R,9S,12R,18S,19S,20S,21S,23R)-1-Hydroxy-12-[(E)-2-((1R,3R,4R)-4-hydroxy-3-methoxy-cyclohexyl)-1-methyl-vinyl]-18-isopropyl-19,21-dimethoxy-13,13,23-trimethyl-11,17,24-trioxa-4-aza-tricyclo[18.3.1.04,9]tetracos-14-ene-2,3,10,16-tetraone

英文名称

(E)-(1R,9S,12R,18S,19S,20S,21S,23R)-1-Hydroxy-12-[(E)-2-((1R,3R,4R)-4-hydroxy-3-methoxy-cyclohexyl)-1-methyl-vinyl]-18-isopropyl-19,21-dimethoxy-13,13,23-trimethyl-11,17,24-trioxa-4-aza-tricyclo[18.3.1.04,9]tetracos-14-ene-2,3,10,16-tetraone

中文别名

英文别名

CAS号

131190-66-4

分子式

C38H59NO12

分子量

721.875

精确质量

721.404

PSA

167.36

LOGP

3.216

合成路线

<1(1R,3R,4R),1E,3(2S),3S>-3-<<<-N-(tert-butoxycarbonyl)piperidin-2-yl>carbonyl>oxy>-5-<(4-methoxybenzyl)oxy>-1-<3-methoxy-4-<(triisopropylsilyl)oxy>cyclohex-1-yl>-2,4,4-trimethyl-1-pentene

<1(1R,3R,4R),1E,3(2S),3S>-3-<<<-N-(tert-butoxycarbonyl)piperidin-2-yl>carbonyl>oxy>-5-<(4-methoxybenzyl)oxy>-1-<3-methoxy-4-<(triisopropylsilyl)oxy>cyclohex-1-yl>-2,4,4-trimethyl-1-pentene

(E)-(1R,9S,12R,18S,19S,20S,21S,23R)-1-Hydroxy-12-[(E)-2-((1R,3R,4R)-4-hydroxy-3-methoxy-cyclohexyl)-1-methyl-vinyl]-18-isopropyl-19,21-dimethoxy-13,13,23-trimethyl-11,17,24-trioxa-4-aza-tricyclo[18.3.1.04,9]tetracos-14-ene-2,3,10,16-tetraone

(E)-(1R,9S,12R,18S,19S,20S,21S,23R)-1-Hydroxy-12-[(E)-2-((1R,3R,4R)-4-hydroxy-3-methoxy-cyclohexyl)-1-methyl-vinyl]-18-isopropyl-19,21-dimethoxy-13,13,23-trimethyl-11,17,24-trioxa-4-aza-tricyclo[18.3.1.04,9]tetracos-14-ene-2,3,10,16-tetraone

上游原料

共找到10个上游原料 >

(2S,3R,4R,6S,7S,8S,9S)-7-<(tert-butyldimethylsilyl)oxy>-2,3,9-trihydroxy-6,8-dimethoxy-4,10-dimethylundecanoic acid methyl ester

(2S,3R,4R,6S,7S,8S,9S)-7-<(tert-butyldimethylsilyl)oxy>-2,3,9-trihydroxy-6,8-dimethoxy-4,10-dimethylundecanoic acid methyl ester

<1(1R,3R,4R),1E,3(2S),3S>-3-<(piperidin-2-ylcarbonyl)oxy>-5-<(trimethylsilyl)oxy>-1-<3-methoxy-4-<(triisopropylsilyl)oxy>cyclohex-1-yl>-2,4,4-trimethyl-1-pentene

<1(1R,3R,4R),1E,3(2S),3S>-3-<(piperidin-2-ylcarbonyl)oxy>-5-<(trimethylsilyl)oxy>-1-<3-methoxy-4-<(triisopropylsilyl)oxy>cyclohex-1-yl>-2,4,4-trimethyl-1-pentene

(2S,3R,4R,6S,7S,8S,9S)-7-<(tert-butyldimethylsilyl)oxy>-2,3-dihydroxy-6,8-dimethoxy-4,10-dimethyl-9-(phenylmethoxy)undecanoic acid methyl ester

(2S,3R,4R,6S,7S,8S,9S)-7-<(tert-butyldimethylsilyl)oxy>-2,3-dihydroxy-6,8-dimethoxy-4,10-dimethyl-9-(phenylmethoxy)undecanoic acid methyl ester

(2E,6S,7S,8R,9S)-7-hydroxy-6,8-dimethoxy-4,10-dimethyl-9-(phenylmethoxy)-2-undecenoic acid methyl ester

(2E,6S,7S,8R,9S)-7-hydroxy-6,8-dimethoxy-4,10-dimethyl-9-(phenylmethoxy)-2-undecenoic acid methyl ester

<2R,S,3R,5S,6S,6(1S,2S)>-2-hydroxy-6-<2-(benzyloxy)-1-methoxy-3-methylbutyl>-5-methoxy-3-methyltetrahydropyran

<2R,S,3R,5S,6S,6(1S,2S)>-2-hydroxy-6-<2-(benzyloxy)-1-methoxy-3-methylbutyl>-5-methoxy-3-methyltetrahydropyran

<1(1R,3R,4R),1E,3(2S),3S>-3-<<<-N-(tert-butoxycarbonyl)piperidin-2-yl>carbonyl>oxy>-1-<3-methoxy-4-<(triisopropylsilyl)oxy>cyclohex-1-yl>-2,4,4-trimethyl-1-penten-5-ol

<1(1R,3R,4R),1E,3(2S),3S>-3-<<<-N-(tert-butoxycarbonyl)piperidin-2-yl>carbonyl>oxy>-1-<3-methoxy-4-<(triisopropylsilyl)oxy>cyclohex-1-yl>-2,4,4-trimethyl-1-penten-5-ol

上游原料

(2S,3R,4R,6S,7S,8S,9S)-7-<(tert-butyldimethylsilyl)oxy>-2,3,9-trihydroxy-6,8-dimethoxy-4,10-dimethylundecanoic acid methyl ester <1(1R,3R,4R),1E,3(2S),3S>-3-<(piperidin-2-ylcarbonyl)oxy>-5-<(trimethylsilyl)oxy>-1-<3-methoxy-4-<(triisopropylsilyl)oxy>cyclohex-1-yl>-2,4,4-trimethyl-1-pentene (2S,3R,4R,6S,7S,8S,9S)-7-<(tert-butyldimethylsilyl)oxy>-2,3-dihydroxy-6,8-dimethoxy-4,10-dimethyl-9-(phenylmethoxy)undecanoic acid methyl ester (2E,6S,7S,8R,9S)-7-hydroxy-6,8-dimethoxy-4,10-dimethyl-9-(phenylmethoxy)-2-undecenoic acid methyl ester <2R,S,3R,5S,6S,6(1S,2S)>-2-hydroxy-6-<2-(benzyloxy)-1-methoxy-3-methylbutyl>-5-methoxy-3-methyltetrahydropyran <1(1R,3R,4R),1E,3(2S),3S>-3-<<<-N-(tert-butoxycarbonyl)piperidin-2-yl>carbonyl>oxy>-1-<3-methoxy-4-<(triisopropylsilyl)oxy>cyclohex-1-yl>-2,4,4-trimethyl-1-penten-5-ol <2S,3R,5S,6S,6(1S,2S)>-2,5-dimethoxy-6-<2-(benzyloxy)-1-methoxy-3-methylbutyl>-3-methyltetrahydropyran <1(1R,3R,4R),1E,3(2S),3S>-3-<<<-N-(tert-butoxycarbonyl)piperidin-2-yl>carbonyl>oxy>-5-<(4-methoxybenzyl)oxy>-1-<3-methoxy-4-<(triisopropylsilyl)oxy>cyclohex-1-yl>-2,4,4-trimethyl-1-pentene (2S,3R,4R,6S,7S,8S,9S)-7-<(tert-butyldimethylsilyl)oxy>-9-<2-(diethylphosphono)acetoxy>-6,8-dimethoxy-2,3-<<(4-methoxyphenyl)methylene>dioxy>-4,10-dimethylundecanoic acid methyl ester