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tert-butyl N-[(10R,14S)-5-[(methoxycarbonyl)amino]-10-methyl-9-oxo-16-{[2-(trimethylsilyl)ethoxy]methyl}-8,16,18- triazatricyclo[13.2.1.02'7]octadeca-1(17),2,4,6,15(18)-pentaen-14-yl]carbamate
CAS号:1329169-72-3
英文名:tert-butyl N-[(10R,14S)-5-[(methoxycarbonyl)amino]-10-methyl-9-oxo-16-{[2-(trimethylsilyl)ethoxy]methyl}-8,16,18- triazatricyclo[13.2.1.02'7]octadeca-1(17),2,4,6,15(18)-pentaen-14-yl]carbamate
分子式:C29H45N5O6Si
分子量:587.783
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合成路线
1422510-93-7
tert-butyl N-[(1S)-1-(4-{4-[(methoxycarbonyl)amino]-2-[(2R)-2-methylbut-3-enamido]phenyl}-1-{[2-(trimethylsilyl)ethoxy]methyl}-1H-imidazol-2-yl)but-3-en-1-yl]carbamate
1329169-72-3
tert-butyl N-[(10R,14S)-5-[(methoxycarbonyl)amino]-10-methyl-9-oxo-16-{[2-(trimethylsilyl)ethoxy]methyl}-8,16,18- triazatricyclo[13.2.1.02'7]octadeca-1(17),2,4,6,15(18)-pentaen-14-yl]carbamate
1329167-28-3
{3-bromo-4-[2-((S)-1-tert-butoxycarbonylaminobut-3-enyl)-3H-imidazol-4-yl]phenyl}carbamic acid methyl ester
1329169-72-3
tert-butyl N-[(10R,14S)-5-[(methoxycarbonyl)amino]-10-methyl-9-oxo-16-{[2-(trimethylsilyl)ethoxy]methyl}-8,16,18- triazatricyclo[13.2.1.02'7]octadeca-1(17),2,4,6,15(18)-pentaen-14-yl]carbamate
1329169-69-8
(6S)-6-((tert-butoxycarbonyl)amino)-6-(4-(4-((methoxycarbonyl)amino)-2-(2,2,2-trifluoroacetamido)phenyl)-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-imidazol-2-yl)-2-methylhexanoic acid
1329169-72-3
tert-butyl N-[(10R,14S)-5-[(methoxycarbonyl)amino]-10-methyl-9-oxo-16-{[2-(trimethylsilyl)ethoxy]methyl}-8,16,18- triazatricyclo[13.2.1.02'7]octadeca-1(17),2,4,6,15(18)-pentaen-14-yl]carbamate
上游原料
(6S)-6-((tert-butoxycarbonyl)amino)-6-(4-(4-((methoxycarbonyl)amino)-2-(2,2,2-trifluoroacetamido)phenyl)-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-imidazol-2-yl)-2-methylhexanoic acid
tert-butyl N-[(1S)-1-(4-{4-[(methoxycarbonyl)amino]-2-[(2R)-2-methylbut-3-enamido]phenyl}-1-{[2-(trimethylsilyl)ethoxy]methyl}-1H-imidazol-2-yl)but-3-en-1-yl]carbamate
{3-bromo-4-[2-((S)-1-tert-butoxycarbonylaminobut-3-enyl)-3H-imidazol-4-yl]phenyl}carbamic acid methyl ester
下游产品
methyl N-[(10R,14S)-14-[6-(2-fluoro-3-methoxyphenyl)-2-oxo-1,3-oxazinan-3-yl]-10-methyl-9-oxo-8,16,18-triazatricyclo[13.2.1.02,7]octadeca-1(17),2,4,6,15(18)-pentaen-5-yl]carbamate trifluoroacetate
methyl N-[(10R,14S)-14-[(6R)-6-(3-chloro-2,6-difluorophenyl)-2-oxo-1,3-oxazinan-3-yl]-10-methyl-9-oxo-8,16,18-triazatricyclo[13.2.1.02,7]octadeca-1(17),2,4,6,15(18)-pentaen-5-yl]carbamate
methyl N-[(10R,14S)-14-[(4S)-4-(3-chloro-2-fluoro-6-methoxyphenyl)-2-oxo-1,3-diazinan-1-yl]-10-methyl-9-oxo-8,16,18-triazatricyclo[13.2.1.02,7]octadeca-1(17),2,4,6,15(18)-pentaen-5-yl]carbamate trifluoroacetate
methyl N-[(10R,14S)-14-[6-(3-chloro-2,6-difluorophenyl)-2-oxo-1,3-oxazinan-3-yl]-10-methyl-9-oxo-16-{[2-(trimethylsilyl)ethoxy]methyl}-8,16,18-triazatricyclo[13.2.1.02,7]octadeca-1(17),2,4,6,15(18)-pentaen-5-yl]carbamate
tert-butyl 4-(4-(((5R,9S,Z)-24-((methoxycarbonyl)amino)-5-methyl-4-oxo-11-((2-(trimethylsilyl)ethoxy)methyl)-11H-3-aza-1(4,2)-imidazola-2(1,2)-benzenacyclononaphane-9-yl)carbamoyl)-1H-1,2,3-triazol-1-yl)piperidine-1-carboxylate
methyl N-[(10R,14S)-14-[6-(2-fluoro-3-methoxyphenyl)-2-oxo-1,3-oxazinan-3-yl]-10-methyl-9-oxo-16-{[2-(trimethylsilyl)ethoxy]methyl}-8,16,18-triazatricyclo[13.2.1.02,7]octadeca-1(17),2,4,6,15(18)-pentaen-5-yl]carbamate
methyl N-[(10R,14S)-14-{[3-(3-chloro-2,6-difluorophenyl)-3-hydroxypropyl]amino}-10-methyl-9-oxo-16-{[2-(trimethylsilyl)ethoxy]methyl}-8,16,18-triazatricyclo[13.2.1.02,7]octadeca-1(17),2,4,6,15(18)-pentaen-5-yl]carbamate
phenyl N-[(1S)-1-(3-chloro-2-fluoro-6-methoxyphenyl)-3-{[(10R,14S)-5-[(methoxycarbonyl)amino]-10-methyl-9-oxo-8,16,18-triazatricyclo[13.2.1.02,7]octadeca-1(17),2,4,6,15(18)-pentaen-14-yl]amino}propyl]carbamate
phenyl ((R)-3-((tert-butyldimethylsilyl)oxy)-3-(4-chloro-3-fluoropyridin-2-yl)propyl)((5R,9S,Z)-24-((methoxycarbonyl)amino)-5-methyl-4-oxo-11-((2-(trimethylsilyl)ethoxy)methyl)-11H-3-aza-1(4,2)-imidazola-2(1,2)-benzenacyclononaphane-9-yl)carbamate
methyl ((5R,9S,Z)-9-(4-(4-chloro-3-fluoropyridin-2-yl)-2-oxotetrahydropyrimidin-1(2H)-yl)-5-methyl-4-oxo-11H-3-aza-1(4,2)-imidazola-2(1,2)-benzenacyclononaphane-24-yl)carbamate