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tert-butyl N-[(10R,14S)-5-[(methoxycarbonyl)amino]-10-methyl-9-oxo-16-{[2-(trimethylsilyl)ethoxy]methyl}-8,16,18- triazatricyclo[13.2.1.02'7]octadeca-1(17),2,4,6,15(18)-pentaen-14-yl]carbamate

tert-butyl N-[(10R,14S)-5-[(methoxycarbonyl)amino]-10-methyl-9-oxo-16-{[2-(trimethylsilyl)ethoxy]methyl}-8,16,18- triazatricyclo[13.2.1.02'7]octadeca-1(17),2,4,6,15(18)-pentaen-14-yl]carbamate

CAS号：1329169-72-3

英文名：tert-butyl N-[(10R,14S)-5-[(methoxycarbonyl)amino]-10-methyl-9-oxo-16-{[2-(trimethylsilyl)ethoxy]methyl}-8,16,18- triazatricyclo[13.2.1.02'7]octadeca-1(17),2,4,6,15(18)-pentaen-14-yl]carbamate

分子式

C29H45N5O6Si

熔点

密度

分子量

587.783

沸点

溶解度

信号词

危险品标志

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基本信息

中文名称

tert-butyl N-[(10R,14S)-5-[(methoxycarbonyl)amino]-10-methyl-9-oxo-16-{[2-(trimethylsilyl)ethoxy]methyl}-8,16,18- triazatricyclo[13.2.1.02'7]octadeca-1(17),2,4,6,15(18)-pentaen-14-yl]carbamate

英文名称

tert-butyl N-[(10R,14S)-5-[(methoxycarbonyl)amino]-10-methyl-9-oxo-16-{[2-(trimethylsilyl)ethoxy]methyl}-8,16,18- triazatricyclo[13.2.1.02'7]octadeca-1(17),2,4,6,15(18)-pentaen-14-yl]carbamate

中文别名

英文别名

tert-butyl methyl N,N\'-((3R,7S)-3-methyl-2-oxo-9-((2-(trimethylsilyl)ethoxy)methyl)-1,2,3,4,5,6,7,9-octahydro-11,8-(azeno)-1,9-benzodiazacyclotridecine-7,14-diyl)biscarbamate、tert-butyl N-[(10R,14S)-5-[(methoxycarbonyl)amino]-10-methyl-9-oxo-16-{[2-(trimethylsilyl)ethoxy]methyl}-8,16,18-triazatricyclo[13.2.1.02,7]octadeca-1(17),2,4,6,15(18)-pentaen-14-yl]carbamate、[(10R,14S)-5-methoxycarbonylamino-10-methyl-9-oxo-16-(2-trimethylsilanylethoxymethyl)-8,16,18-triazatricyclo[13.2.1.0(2,7)]octadeca-1(17),2,4,6,15(18)-pentaen-14-yl]carbamic acid tert-butyl ester

CAS号

1329169-72-3

分子式

C29H45N5O6Si

分子量

587.783

精确质量

587.314

PSA

132.81

LOGP

6.9669

合成路线

共找到10条合成路线 >

tert-butyl N-[(1S)-1-(4-{4-[(methoxycarbonyl)amino]-2-[(2R)-2-methylbut-3-enamido]phenyl}-1-{[2-(trimethylsilyl)ethoxy]methyl}-1H-imidazol-2-yl)but-3-en-1-yl]carbamate

tert-butyl N-[(1S)-1-(4-{4-[(methoxycarbonyl)amino]-2-[(2R)-2-methylbut-3-enamido]phenyl}-1-{[2-(trimethylsilyl)ethoxy]methyl}-1H-imidazol-2-yl)but-3-en-1-yl]carbamate

tert-butyl N-[(10R,14S)-5-[(methoxycarbonyl)amino]-10-methyl-9-oxo-16-{[2-(trimethylsilyl)ethoxy]methyl}-8,16,18- triazatricyclo[13.2.1.02'7]octadeca-1(17),2,4,6,15(18)-pentaen-14-yl]carbamate

tert-butyl N-[(10R,14S)-5-[(methoxycarbonyl)amino]-10-methyl-9-oxo-16-{[2-(trimethylsilyl)ethoxy]methyl}-8,16,18- triazatricyclo[13.2.1.02'7]octadeca-1(17),2,4,6,15(18)-pentaen-14-yl]carbamate

上游原料

共找到3个上游原料 >

(6S)-6-((tert-butoxycarbonyl)amino)-6-(4-(4-((methoxycarbonyl)amino)-2-(2,2,2-trifluoroacetamido)phenyl)-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-imidazol-2-yl)-2-methylhexanoic acid

(6S)-6-((tert-butoxycarbonyl)amino)-6-(4-(4-((methoxycarbonyl)amino)-2-(2,2,2-trifluoroacetamido)phenyl)-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-imidazol-2-yl)-2-methylhexanoic acid

tert-butyl N-[(1S)-1-(4-{4-[(methoxycarbonyl)amino]-2-[(2R)-2-methylbut-3-enamido]phenyl}-1-{[2-(trimethylsilyl)ethoxy]methyl}-1H-imidazol-2-yl)but-3-en-1-yl]carbamate

tert-butyl N-[(1S)-1-(4-{4-[(methoxycarbonyl)amino]-2-[(2R)-2-methylbut-3-enamido]phenyl}-1-{[2-(trimethylsilyl)ethoxy]methyl}-1H-imidazol-2-yl)but-3-en-1-yl]carbamate

{3-bromo-4-[2-((S)-1-tert-butoxycarbonylaminobut-3-enyl)-3H-imidazol-4-yl]phenyl}carbamic acid methyl ester

{3-bromo-4-[2-((S)-1-tert-butoxycarbonylaminobut-3-enyl)-3H-imidazol-4-yl]phenyl}carbamic acid methyl ester

下游产品

共找到10个下游商品 >

methyl N-[(10R,14S)-14-[6-(2-fluoro-3-methoxyphenyl)-2-oxo-1,3-oxazinan-3-yl]-10-methyl-9-oxo-8,16,18-triazatricyclo[13.2.1.02,7]octadeca-1(17),2,4,6,15(18)-pentaen-5-yl]carbamate trifluoroacetate

methyl N-[(10R,14S)-14-[6-(2-fluoro-3-methoxyphenyl)-2-oxo-1,3-oxazinan-3-yl]-10-methyl-9-oxo-8,16,18-triazatricyclo[13.2.1.02,7]octadeca-1(17),2,4,6,15(18)-pentaen-5-yl]carbamate trifluoroacetate

methyl N-[(10R,14S)-14-[(6R)-6-(3-chloro-2,6-difluorophenyl)-2-oxo-1,3-oxazinan-3-yl]-10-methyl-9-oxo-8,16,18-triazatricyclo[13.2.1.02,7]octadeca-1(17),2,4,6,15(18)-pentaen-5-yl]carbamate

methyl N-[(10R,14S)-14-[(6R)-6-(3-chloro-2,6-difluorophenyl)-2-oxo-1,3-oxazinan-3-yl]-10-methyl-9-oxo-8,16,18-triazatricyclo[13.2.1.02,7]octadeca-1(17),2,4,6,15(18)-pentaen-5-yl]carbamate

methyl N-[(10R,14S)-14-[(4S)-4-(3-chloro-2-fluoro-6-methoxyphenyl)-2-oxo-1,3-diazinan-1-yl]-10-methyl-9-oxo-8,16,18-triazatricyclo[13.2.1.02,7]octadeca-1(17),2,4,6,15(18)-pentaen-5-yl]carbamate trifluoroacetate

methyl N-[(10R,14S)-14-[(4S)-4-(3-chloro-2-fluoro-6-methoxyphenyl)-2-oxo-1,3-diazinan-1-yl]-10-methyl-9-oxo-8,16,18-triazatricyclo[13.2.1.02,7]octadeca-1(17),2,4,6,15(18)-pentaen-5-yl]carbamate trifluoroacetate

methyl N-[(10R,14S)-14-[6-(3-chloro-2,6-difluorophenyl)-2-oxo-1,3-oxazinan-3-yl]-10-methyl-9-oxo-16-{[2-(trimethylsilyl)ethoxy]methyl}-8,16,18-triazatricyclo[13.2.1.02,7]octadeca-1(17),2,4,6,15(18)-pentaen-5-yl]carbamate

methyl N-[(10R,14S)-14-[6-(3-chloro-2,6-difluorophenyl)-2-oxo-1,3-oxazinan-3-yl]-10-methyl-9-oxo-16-{[2-(trimethylsilyl)ethoxy]methyl}-8,16,18-triazatricyclo[13.2.1.02,7]octadeca-1(17),2,4,6,15(18)-pentaen-5-yl]carbamate

tert-butyl 4-(4-(((5R,9S,Z)-24-((methoxycarbonyl)amino)-5-methyl-4-oxo-11-((2-(trimethylsilyl)ethoxy)methyl)-11H-3-aza-1(4,2)-imidazola-2(1,2)-benzenacyclononaphane-9-yl)carbamoyl)-1H-1,2,3-triazol-1-yl)piperidine-1-carboxylate

tert-butyl 4-(4-(((5R,9S,Z)-24-((methoxycarbonyl)amino)-5-methyl-4-oxo-11-((2-(trimethylsilyl)ethoxy)methyl)-11H-3-aza-1(4,2)-imidazola-2(1,2)-benzenacyclononaphane-9-yl)carbamoyl)-1H-1,2,3-triazol-1-yl)piperidine-1-carboxylate

methyl N-[(10R,14S)-14-[6-(2-fluoro-3-methoxyphenyl)-2-oxo-1,3-oxazinan-3-yl]-10-methyl-9-oxo-16-{[2-(trimethylsilyl)ethoxy]methyl}-8,16,18-triazatricyclo[13.2.1.02,7]octadeca-1(17),2,4,6,15(18)-pentaen-5-yl]carbamate

methyl N-[(10R,14S)-14-[6-(2-fluoro-3-methoxyphenyl)-2-oxo-1,3-oxazinan-3-yl]-10-methyl-9-oxo-16-{[2-(trimethylsilyl)ethoxy]methyl}-8,16,18-triazatricyclo[13.2.1.02,7]octadeca-1(17),2,4,6,15(18)-pentaen-5-yl]carbamate

上游原料

(6S)-6-((tert-butoxycarbonyl)amino)-6-(4-(4-((methoxycarbonyl)amino)-2-(2,2,2-trifluoroacetamido)phenyl)-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-imidazol-2-yl)-2-methylhexanoic acid tert-butyl N-[(1S)-1-(4-{4-[(methoxycarbonyl)amino]-2-[(2R)-2-methylbut-3-enamido]phenyl}-1-{[2-(trimethylsilyl)ethoxy]methyl}-1H-imidazol-2-yl)but-3-en-1-yl]carbamate {3-bromo-4-[2-((S)-1-tert-butoxycarbonylaminobut-3-enyl)-3H-imidazol-4-yl]phenyl}carbamic acid methyl ester

下游产品

methyl N-[(10R,14S)-14-[6-(2-fluoro-3-methoxyphenyl)-2-oxo-1,3-oxazinan-3-yl]-10-methyl-9-oxo-8,16,18-triazatricyclo[13.2.1.02,7]octadeca-1(17),2,4,6,15(18)-pentaen-5-yl]carbamate trifluoroacetate methyl N-[(10R,14S)-14-[(6R)-6-(3-chloro-2,6-difluorophenyl)-2-oxo-1,3-oxazinan-3-yl]-10-methyl-9-oxo-8,16,18-triazatricyclo[13.2.1.02,7]octadeca-1(17),2,4,6,15(18)-pentaen-5-yl]carbamate methyl N-[(10R,14S)-14-[(4S)-4-(3-chloro-2-fluoro-6-methoxyphenyl)-2-oxo-1,3-diazinan-1-yl]-10-methyl-9-oxo-8,16,18-triazatricyclo[13.2.1.02,7]octadeca-1(17),2,4,6,15(18)-pentaen-5-yl]carbamate trifluoroacetate methyl N-[(10R,14S)-14-[6-(3-chloro-2,6-difluorophenyl)-2-oxo-1,3-oxazinan-3-yl]-10-methyl-9-oxo-16-{[2-(trimethylsilyl)ethoxy]methyl}-8,16,18-triazatricyclo[13.2.1.02,7]octadeca-1(17),2,4,6,15(18)-pentaen-5-yl]carbamate tert-butyl 4-(4-(((5R,9S,Z)-24-((methoxycarbonyl)amino)-5-methyl-4-oxo-11-((2-(trimethylsilyl)ethoxy)methyl)-11H-3-aza-1(4,2)-imidazola-2(1,2)-benzenacyclononaphane-9-yl)carbamoyl)-1H-1,2,3-triazol-1-yl)piperidine-1-carboxylate methyl N-[(10R,14S)-14-[6-(2-fluoro-3-methoxyphenyl)-2-oxo-1,3-oxazinan-3-yl]-10-methyl-9-oxo-16-{[2-(trimethylsilyl)ethoxy]methyl}-8,16,18-triazatricyclo[13.2.1.02,7]octadeca-1(17),2,4,6,15(18)-pentaen-5-yl]carbamate methyl N-[(10R,14S)-14-{[3-(3-chloro-2,6-difluorophenyl)-3-hydroxypropyl]amino}-10-methyl-9-oxo-16-{[2-(trimethylsilyl)ethoxy]methyl}-8,16,18-triazatricyclo[13.2.1.02,7]octadeca-1(17),2,4,6,15(18)-pentaen-5-yl]carbamate phenyl N-[(1S)-1-(3-chloro-2-fluoro-6-methoxyphenyl)-3-{[(10R,14S)-5-[(methoxycarbonyl)amino]-10-methyl-9-oxo-8,16,18-triazatricyclo[13.2.1.02,7]octadeca-1(17),2,4,6,15(18)-pentaen-14-yl]amino}propyl]carbamate phenyl ((R)-3-((tert-butyldimethylsilyl)oxy)-3-(4-chloro-3-fluoropyridin-2-yl)propyl)((5R,9S,Z)-24-((methoxycarbonyl)amino)-5-methyl-4-oxo-11-((2-(trimethylsilyl)ethoxy)methyl)-11H-3-aza-1(4,2)-imidazola-2(1,2)-benzenacyclononaphane-9-yl)carbamate methyl ((5R,9S,Z)-9-(4-(4-chloro-3-fluoropyridin-2-yl)-2-oxotetrahydropyrimidin-1(2H)-yl)-5-methyl-4-oxo-11H-3-aza-1(4,2)-imidazola-2(1,2)-benzenacyclononaphane-24-yl)carbamate