化合物简介
Mazapertine (RWJ-37796) is an antipsychotic agent that was developed by Johnson & Johnson but never marketed. It exerts its pharmacological effect through affinity for dopamine D2, serotonin 5-HT1A, and α1-adrenergic receptors.
基本信息
中文名称
马扎哌汀
英文名称
piperidin-1-yl-[3-[[4-(2-propan-2-yloxyphenyl)piperazin-1-yl]methyl]phenyl]methanone
中文别名
英文别名
UNII-N0X1XW704P、[3-[[4-[2-(1-Methylethoxy)phenyl]-1-piperazinyl]methyl]benzoyl]-piperidine、Mazapertine、Mazapertine [INN]、1-[3-[[4-[2-(1-methylethoxy)phenyl]-1-piperazinyl]methyl]benzoyl]piperidine
CAS号
134208-17-6
分子式
C26H35N3O2
分子量
421.575
精确质量
421.273
PSA
36.02
LOGP
4.3629
物化性质
密度
1.128g/cm3
沸点
583.8ºC at 760 mmHg
闪点
306.9ºC
折射率
1.584
蒸汽压
1.29E-13mmHg at 25°C
