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阿托伐他汀叔丁酯
CAS号:134395-00-9
英文名:tert-butyl (3R,5R)-7-[2-(4-fluorophenyl)-3-phenyl-4-(phenylcarbamoyl)-5-propan-2-ylpyrrol-1-yl]-3,5-dihydroxyheptanoate
分子式:C37H43FN2O5
分子量:614.746
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合成路线
125971-95-1
(4R-cis)-6-[2-[2-(4-氟苯基)-5-(1-异丙基)-3-苯基-4-[(苯胺)羰基]-1H-吡咯-1-基]乙基]-2,2-二甲基-1,3-二氧己环-4-乙酸叔丁酯
125995-03-1
阿托伐他汀内酯
134395-00-9
阿托伐他汀叔丁酯
1035204-90-0
tert-butyl 2-((2R,4R)-4-(2-(2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl)ethyl)-1,5-dioxaspiro[5.5]undecan-2-yl)acetate
134395-00-9
阿托伐他汀叔丁酯
100-52-7
苯甲醛
134395-00-9
阿托伐他汀叔丁酯
125971-57-5
4-甲基-3-氧代-N-苯基-2-(苯甲烯基)戊酰胺
134395-00-9
阿托伐他汀叔丁酯
74497-02-2
134395-00-9
阿托伐他汀叔丁酯
1447820-16-7
(S)-N,N-diallyl-3-hydroxy-5-(trityloxy)pentanethioamide
134395-00-9
阿托伐他汀叔丁酯
1447820-18-9
(R)-5-(diallylamino)pentane-1,3-diol
134395-00-9
阿托伐他汀叔丁酯
1447820-21-4
(R)-1-(diallylamino)-5-(trityloxy)pentan-3-ol
134395-00-9
阿托伐他汀叔丁酯
1331869-16-9
(R)-N,N-diallyl-5-(benzyloxy)-3-hydroxypentanethioamide
134395-00-9
阿托伐他汀叔丁酯
1347738-07-1
(R)-N,N-diallyl-5-(benzyloxy)-3-((tert-butyldimethylsilyl)oxy)pentanethioamide
134395-00-9
阿托伐他汀叔丁酯
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上游原料
tert-butyl 2-((2R,4R,6R)-6-(2-aminoethyl)-2-phenyl-1,3-dioxan-4-yl)acetate
tert-butyl 2-((4R,6R)-6-(2-azidoethyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate
(R)-1-(diallylamino)-5-(trityloxy)pentan-3-ol
tert-butyl 2-((2R,4R,6R)-6-(2-(2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl)ethyl)-2-phenyl-1,3-dioxan-4-yl)acetate
tert-butyl 2-((4R,6R)-6-(2-(benzyloxy)ethyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate
tert-butyl 2-[(4R,6R)-6-(2-hydroxyethyl)-2,2-dimethyl-1,3-dioxan-4-yl]acetate
N-苯基异丁酰乙酰胺
(R)-tert-butyl 7-(benzyloxy)-5-((tert-butyldimethylsilyl)oxy)-3-oxoheptanoate
tert-butyl 2-((4R,6R)-2,2-dimethyl-6-(2-(tosyloxy)ethyl)-1,3-dioxan-4-yl)acetate
(R)-N,N-diallyl-5-(benzyloxy)-3-hydroxypentanethioamide
tert-butyl 2-((2R,4R)-4-(2-(2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl)ethyl)-1,5-dioxaspiro[5.5]undecan-2-yl)acetate
tert-butyl 2-((4R,6R)-6-(2-aminoethyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate
对氟苯甲醛
苯甲醛
阿托伐他汀中间体M4
4-甲基-3-氧代-N-苯基-2-(苯甲烯基)戊酰胺
(S)-N,N-diallyl-3-hydroxy-5-(trityloxy)pentanethioamide
(R)-N,N-diallyl-5-(benzyloxy)-3-((tert-butyldimethylsilyl)oxy)pentanethioamide
tert-butyl 2-((2R,4R,6R)-6-(2-(diallylamino)ethyl)-2-phenyl-1,3-dioxan-4-yl)acetate
cis-t-butyl-7-nitro-3,5-dihydroxy-heptanoate
(R)-5-(diallylamino)pentane-1,3-diol
(4R-cis)-6-氰甲基-2,2-二甲基-1,3-二氧六环-4-乙酸叔丁酯
(4R-cis)-6-[2-[2-(4-氟苯基)-5-(1-异丙基)-3-苯基-4-[(苯胺)羰基]-1H-吡咯-1-基]乙基]-2,2-二甲基-1,3-二氧己环-4-乙酸叔丁酯
tert-butyl 2-((7R,9R)-9-(2-(2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl)ethyl)-6,10-dioxaspiro[4.5]decan-7-yl)acetate
下游产品
阿托伐他汀内酯
阿托伐他汀
阿托伐他汀钙
阿伐他汀钠