百科

阿托伐他汀叔丁酯

阿托伐他汀叔丁酯

CAS号：134395-00-9

英文名：tert-butyl (3R,5R)-7-[2-(4-fluorophenyl)-3-phenyl-4-(phenylcarbamoyl)-5-propan-2-ylpyrrol-1-yl]-3,5-dihydroxyheptanoate

分子式

C37H43FN2O5

熔点

66-68ºC

密度

分子量

614.746

沸点

溶解度

信号词

危险品标志

若想填写更详细的询价信息，请点击进入询价页面

点我

化合物简介

An impurity arising in the synthesis of Atorvastatin.

基本信息

中文名称

阿托伐他汀叔丁酯

英文名称

tert-butyl (3R,5R)-7-[2-(4-fluorophenyl)-3-phenyl-4-(phenylcarbamoyl)-5-propan-2-ylpyrrol-1-yl]-3,5-dihydroxyheptanoate

中文别名

阿托伐他汀叔丁基酯

英文别名

Atorvastatin tert-Butyl Ester、(3R,5R)-tert-Butyl 7-(2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl)-3,5-dihydroxyheptanoate、tert-butyl (3R,5R)-7-[2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)pyrrol-1-yl]-3,5-dihydroxyheptanoate、(|AR,|AR)-2-(4-Fluorophenyl)-|A,|A-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrole-1-heptanoic Acid 1,1-Dimethylethyl Ester

CAS号

134395-00-9

分子式

C37H43FN2O5

分子量

614.746

精确质量

614.316

PSA

100.79

LOGP

7.6437

编号系统

EINECS号

603-817-6

物化性质

熔点

66-68ºC

安全信息

海关编码

2934999090

合成路线

共找到5条合成路线 >

(4R-cis)-6-[2-[2-(4-氟苯基)-5-(1-异丙基)-3-苯基-4-[(苯胺)羰基]-1H-吡咯-1-基]乙基]-2,2-二甲基-1,3-二氧己环-4-乙酸叔丁酯

(4R-cis)-6-[2-[2-(4-氟苯基)-5-(1-异丙基)-3-苯基-4-[(苯胺)羰基]-1H-吡咯-1-基]乙基]-2,2-二甲基-1,3-二氧己环-4-乙酸叔丁酯

阿托伐他汀内酯

阿托伐他汀内酯

阿托伐他汀叔丁酯

阿托伐他汀叔丁酯

上游原料

共找到25个上游原料 >

tert-butyl 2-((2R,4R,6R)-6-(2-aminoethyl)-2-phenyl-1,3-dioxan-4-yl)acetate

tert-butyl 2-((2R,4R,6R)-6-(2-aminoethyl)-2-phenyl-1,3-dioxan-4-yl)acetate

tert-butyl 2-((4R,6R)-6-(2-azidoethyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate

tert-butyl 2-((4R,6R)-6-(2-azidoethyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate

(R)-1-(diallylamino)-5-(trityloxy)pentan-3-ol

(R)-1-(diallylamino)-5-(trityloxy)pentan-3-ol

tert-butyl 2-((2R,4R,6R)-6-(2-(2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl)ethyl)-2-phenyl-1,3-dioxan-4-yl)acetate

tert-butyl 2-((2R,4R,6R)-6-(2-(2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl)ethyl)-2-phenyl-1,3-dioxan-4-yl)acetate

tert-butyl 2-((4R,6R)-6-(2-(benzyloxy)ethyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate

tert-butyl 2-((4R,6R)-6-(2-(benzyloxy)ethyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate

tert-butyl 2-[(4R,6R)-6-(2-hydroxyethyl)-2,2-dimethyl-1,3-dioxan-4-yl]acetate

tert-butyl 2-[(4R,6R)-6-(2-hydroxyethyl)-2,2-dimethyl-1,3-dioxan-4-yl]acetate

下游产品

共找到4个下游商品 >

阿托伐他汀内酯

阿托伐他汀内酯

阿托伐他汀

阿托伐他汀

阿托伐他汀钙

阿托伐他汀钙

阿伐他汀钠

阿伐他汀钠

上游原料

tert-butyl 2-((2R,4R,6R)-6-(2-aminoethyl)-2-phenyl-1,3-dioxan-4-yl)acetate tert-butyl 2-((4R,6R)-6-(2-azidoethyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate (R)-1-(diallylamino)-5-(trityloxy)pentan-3-ol tert-butyl 2-((2R,4R,6R)-6-(2-(2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl)ethyl)-2-phenyl-1,3-dioxan-4-yl)acetate tert-butyl 2-((4R,6R)-6-(2-(benzyloxy)ethyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate tert-butyl 2-[(4R,6R)-6-(2-hydroxyethyl)-2,2-dimethyl-1,3-dioxan-4-yl]acetate N-苯基异丁酰乙酰胺 (R)-tert-butyl 7-(benzyloxy)-5-((tert-butyldimethylsilyl)oxy)-3-oxoheptanoate tert-butyl 2-((4R,6R)-2,2-dimethyl-6-(2-(tosyloxy)ethyl)-1,3-dioxan-4-yl)acetate (R)-N,N-diallyl-5-(benzyloxy)-3-hydroxypentanethioamide tert-butyl 2-((2R,4R)-4-(2-(2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl)ethyl)-1,5-dioxaspiro[5.5]undecan-2-yl)acetate tert-butyl 2-((4R,6R)-6-(2-aminoethyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate 对氟苯甲醛苯甲醛阿托伐他汀中间体M4 4-甲基-3-氧代-N-苯基-2-(苯甲烯基)戊酰胺 (S)-N,N-diallyl-3-hydroxy-5-(trityloxy)pentanethioamide (R)-N,N-diallyl-5-(benzyloxy)-3-((tert-butyldimethylsilyl)oxy)pentanethioamide tert-butyl 2-((2R,4R,6R)-6-(2-(diallylamino)ethyl)-2-phenyl-1,3-dioxan-4-yl)acetate cis-t-butyl-7-nitro-3,5-dihydroxy-heptanoate (R)-5-(diallylamino)pentane-1,3-diol (4R-cis)-6-氰甲基-2,2-二甲基-1,3-二氧六环-4-乙酸叔丁酯 (4R-cis)-6-[2-[2-(4-氟苯基)-5-(1-异丙基)-3-苯基-4-[(苯胺)羰基]-1H-吡咯-1-基]乙基]-2,2-二甲基-1,3-二氧己环-4-乙酸叔丁酯 tert-butyl 2-((7R,9R)-9-(2-(2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl)ethyl)-6,10-dioxaspiro[4.5]decan-7-yl)acetate

下游产品

阿托伐他汀内酯阿托伐他汀阿托伐他汀钙阿伐他汀钠