百科

(3R,5R,8S,9S)-8-((tert-butyldimethylsilyl)oxy)-1-oxo-3-(2-oxoethyl)-3,4,5,6,7,8,9,10-octahydro-1H-5,9-epoxybenzo[c][1]oxacyclododecin-14-yl acetate

(3R,5R,8S,9S)-8-((tert-butyldimethylsilyl)oxy)-1-oxo-3-(2-oxoethyl)-3,4,5,6,7,8,9,10-octahydro-1H-5,9-epoxybenzo[c][1]oxacyclododecin-14-yl acetate

CAS号：1350979-00-8

英文名：(3R,5R,8S,9S)-8-((tert-butyldimethylsilyl)oxy)-1-oxo-3-(2-oxoethyl)-3,4,5,6,7,8,9,10-octahydro-1H-5,9-epoxybenzo[c][1]oxacyclododecin-14-yl acetate

分子式：C25H36O7Si

分子量：476.635

合成路线

(3S,5R,8S,9S)-8-((tert-butyldimethylsilyl)oxy)-3-(2-hydroxyethyl)-1-oxo-3,4,5,6,7,8,9,10-octahydro-1H-5,9-epoxybenzo[c][1]oxacyclododecin-14-yl acetate

(3S,5R,8S,9S)-8-((tert-butyldimethylsilyl)oxy)-3-(2-hydroxyethyl)-1-oxo-3,4,5,6,7,8,9,10-octahydro-1H-5,9-epoxybenzo[c][1]oxacyclododecin-14-yl acetate

(3R,5R,8S,9S)-8-((tert-butyldimethylsilyl)oxy)-1-oxo-3-(2-oxoethyl)-3,4,5,6,7,8,9,10-octahydro-1H-5,9-epoxybenzo[c][1]oxacyclododecin-14-yl acetate

(3R,5R,8S,9S)-8-((tert-butyldimethylsilyl)oxy)-1-oxo-3-(2-oxoethyl)-3,4,5,6,7,8,9,10-octahydro-1H-5,9-epoxybenzo[c][1]oxacyclododecin-14-yl acetate

(3S,5R,8S,9S)-14-(benzyloxy)-3-(2-(benzyloxy)ethyl)-8-((tert-butyldimethylsilyl)oxy)-3,4,5,6,7,8,9,10-octahydro-1H-5,9-epoxybenzo[c][1]oxacyclododecin-1-one

(3S,5R,8S,9S)-14-(benzyloxy)-3-(2-(benzyloxy)ethyl)-8-((tert-butyldimethylsilyl)oxy)-3,4,5,6,7,8,9,10-octahydro-1H-5,9-epoxybenzo[c][1]oxacyclododecin-1-one

(3R,5R,8S,9S)-8-((tert-butyldimethylsilyl)oxy)-1-oxo-3-(2-oxoethyl)-3,4,5,6,7,8,9,10-octahydro-1H-5,9-epoxybenzo[c][1]oxacyclododecin-14-yl acetate

(3R,5R,8S,9S)-8-((tert-butyldimethylsilyl)oxy)-1-oxo-3-(2-oxoethyl)-3,4,5,6,7,8,9,10-octahydro-1H-5,9-epoxybenzo[c][1]oxacyclododecin-14-yl acetate

(3S,5R,8S,9S)-8-((tert-butyldimethylsilyl)oxy)-14-hydroxy-3-(2-hydroxyethyl)-3,4,5,6,7,8,9,10-octahydro-1H-5,9-epoxybenzo[c][1]oxacyclododecin-1-one

(3S,5R,8S,9S)-8-((tert-butyldimethylsilyl)oxy)-14-hydroxy-3-(2-hydroxyethyl)-3,4,5,6,7,8,9,10-octahydro-1H-5,9-epoxybenzo[c][1]oxacyclododecin-1-one

(3R,5R,8S,9S)-8-((tert-butyldimethylsilyl)oxy)-1-oxo-3-(2-oxoethyl)-3,4,5,6,7,8,9,10-octahydro-1H-5,9-epoxybenzo[c][1]oxacyclododecin-14-yl acetate

(3R,5R,8S,9S)-8-((tert-butyldimethylsilyl)oxy)-1-oxo-3-(2-oxoethyl)-3,4,5,6,7,8,9,10-octahydro-1H-5,9-epoxybenzo[c][1]oxacyclododecin-14-yl acetate

上游原料

(3S,5R,8S,9S)-8-((tert-butyldimethylsilyl)oxy)-3-(2-hydroxyethyl)-1-oxo-3,4,5,6,7,8,9,10-octahydro-1H-5,9-epoxybenzo[c][1]oxacyclododecin-14-yl acetate (3S,5R,8S,9S)-8-((tert-butyldimethylsilyl)oxy)-14-hydroxy-3-(2-hydroxyethyl)-3,4,5,6,7,8,9,10-octahydro-1H-5,9-epoxybenzo[c][1]oxacyclododecin-1-one (3S,5R,8S,9S)-14-(benzyloxy)-3-(2-(benzyloxy)ethyl)-8-((tert-butyldimethylsilyl)oxy)-3,4,5,6,7,8,9,10-octahydro-1H-5,9-epoxybenzo[c][1]oxacyclododecin-1-one

下游产品

11-deoxy-10-α-hydroxyapicularen A (2Z,4Z)-N-((E)-3-((3S,5R,8S,9S)-8-((tert-butyldimethylsilyl)oxy)-14-hydroxy-1-oxo-3,4,5,6,7,8,9,10-octahydro-1H-5,9-epoxybenzo[c][1]oxacyclododecin-3-yl)prop-1-en-1-yl)hepta-2,4-dienamide