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(S)-N-(2-(2-(7-(3-aminoazetidin-1-yl)-5-(3-hydroxyazetidin-1-yl)pyrazolo[1,5-a]pyrimidin-2-yl)piperidine-1-carbonyl)-4-chlorophenyl)methanesulfonamide hydrochloride

(S)-N-(2-(2-(7-(3-aminoazetidin-1-yl)-5-(3-hydroxyazetidin-1-yl)pyrazolo[1,5-a]pyrimidin-2-yl)piperidine-1-carbonyl)-4-chlorophenyl)methanesulfonamide hydrochloride

CAS号：1353624-59-5

英文名：(S)-N-(2-(2-(7-(3-aminoazetidin-1-yl)-5-(3-hydroxyazetidin-1-yl)pyrazolo[1,5-a]pyrimidin-2-yl)piperidine-1-carbonyl)-4-chlorophenyl)methanesulfonamide hydrochloride

分子式

C25H32Cl2N8O4S

熔点

密度

分子量

611.544

沸点

溶解度

信号词

危险品标志

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基本信息

中文名称

(S)-N-(2-(2-(7-(3-aminoazetidin-1-yl)-5-(3-hydroxyazetidin-1-yl)pyrazolo[1,5-a]pyrimidin-2-yl)piperidine-1-carbonyl)-4-chlorophenyl)methanesulfonamide hydrochloride

英文名称

(S)-N-(2-(2-(7-(3-aminoazetidin-1-yl)-5-(3-hydroxyazetidin-1-yl)pyrazolo[1,5-a]pyrimidin-2-yl)piperidine-1-carbonyl)-4-chlorophenyl)methanesulfonamide hydrochloride

中文别名

英文别名

CAS号

1353624-59-5

分子式

C25H32Cl2N8O4S

分子量

611.544

精确质量

610.164

PSA

157.78

LOGP

4.1738

合成路线

(S)-5,7-dichloro-2-(piperidin-2-yl)pyrazolo[1,5-a]pyrimidine hydrochloride

(S)-5,7-dichloro-2-(piperidin-2-yl)pyrazolo[1,5-a]pyrimidine hydrochloride

(S)-N-(2-(2-(7-(3-aminoazetidin-1-yl)-5-(3-hydroxyazetidin-1-yl)pyrazolo[1,5-a]pyrimidin-2-yl)piperidine-1-carbonyl)-4-chlorophenyl)methanesulfonamide hydrochloride

(S)-N-(2-(2-(7-(3-aminoazetidin-1-yl)-5-(3-hydroxyazetidin-1-yl)pyrazolo[1,5-a]pyrimidin-2-yl)piperidine-1-carbonyl)-4-chlorophenyl)methanesulfonamide hydrochloride

上游原料

共找到6个上游原料 >

(S)-5,7-dichloro-2-(piperidin-2-yl)pyrazolo[1,5-a]pyrimidine hydrochloride

(S)-5,7-dichloro-2-(piperidin-2-yl)pyrazolo[1,5-a]pyrimidine hydrochloride

(S)-N-(4-chloro-2-(2-(5,7-dichloropyrazolo[1,5-a]pyrimidin-2-yl)piperidine-1-carbonyl)phenyl)methanesulfonamide

(S)-N-(4-chloro-2-(2-(5,7-dichloropyrazolo[1,5-a]pyrimidin-2-yl)piperidine-1-carbonyl)phenyl)methanesulfonamide

tert-butyl (S)-(1-(2-(1-(5-chloro-2-(methylsulfonamido)benzoyl)piperidin-2-yl)-5-(3-hydroxyazetidin-1-yl)pyrazolo[1,5-a]pyrimidin-7-yl)azetidin-3-yl)carbamate

tert-butyl (S)-(1-(2-(1-(5-chloro-2-(methylsulfonamido)benzoyl)piperidin-2-yl)-5-(3-hydroxyazetidin-1-yl)pyrazolo[1,5-a]pyrimidin-7-yl)azetidin-3-yl)carbamate

(S)-tert-butyl 2-(5-Amino-1H-pyrazol-3-yl)piperidine-1-carboxylate

(S)-tert-butyl 2-(5-Amino-1H-pyrazol-3-yl)piperidine-1-carboxylate

tert-butyl (S)-2-(7-hydroxy-5-oxo-4,5-dihydropyrazolo[1,5-a]pyrimidin-2-yl)piperidine-1-carboxylate

tert-butyl (S)-2-(7-hydroxy-5-oxo-4,5-dihydropyrazolo[1,5-a]pyrimidin-2-yl)piperidine-1-carboxylate

tert-butyl (S)-(1-(5-chloro-2-(1-(5-chloro-2-(methylsulfonamido)benzoyl)piperidin-2-yl)pyrazolo[1,5-a]pyrimidin-7-yl)azetidin-3-yl)carbamate

tert-butyl (S)-(1-(5-chloro-2-(1-(5-chloro-2-(methylsulfonamido)benzoyl)piperidin-2-yl)pyrazolo[1,5-a]pyrimidin-7-yl)azetidin-3-yl)carbamate

上游原料

(S)-5,7-dichloro-2-(piperidin-2-yl)pyrazolo[1,5-a]pyrimidine hydrochloride (S)-N-(4-chloro-2-(2-(5,7-dichloropyrazolo[1,5-a]pyrimidin-2-yl)piperidine-1-carbonyl)phenyl)methanesulfonamide tert-butyl (S)-(1-(2-(1-(5-chloro-2-(methylsulfonamido)benzoyl)piperidin-2-yl)-5-(3-hydroxyazetidin-1-yl)pyrazolo[1,5-a]pyrimidin-7-yl)azetidin-3-yl)carbamate (S)-tert-butyl 2-(5-Amino-1H-pyrazol-3-yl)piperidine-1-carboxylate tert-butyl (S)-2-(7-hydroxy-5-oxo-4,5-dihydropyrazolo[1,5-a]pyrimidin-2-yl)piperidine-1-carboxylate tert-butyl (S)-(1-(5-chloro-2-(1-(5-chloro-2-(methylsulfonamido)benzoyl)piperidin-2-yl)pyrazolo[1,5-a]pyrimidin-7-yl)azetidin-3-yl)carbamate