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(S)-5,7-dichloro-2-(piperidin-2-yl)pyrazolo[1,5-a]pyrimidine hydrochloride

(S)-5,7-dichloro-2-(piperidin-2-yl)pyrazolo[1,5-a]pyrimidine hydrochloride

CAS号:1353628-69-9
英文名:(S)-5,7-dichloro-2-(piperidin-2-yl)pyrazolo[1,5-a]pyrimidine hydrochloride
分子式:C11H12Cl2N4
分子量:271.146
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(S)-N-(4-chloro-2-(2-(5-(3-hydroxyazetidin-1-yl)-7-(4-hydroxypiperidin-1-yl)pyrazolo[1,5-a]pyrimidin-2-yl)piperidine-1-carbonyl)phenyl)methanesulfonamide (S)-N-(2-(2-(5-(azetidin-1-yl)-7-(4-(2-fluoroethyl)piperazin-1-yl)pyrazolo[1,5-a]pyrimidin-2-yl)piperidine-1-carbonyl)-4-chlorophenyl)methanesulfonamide (S)-N-(2-(2-(5-(azetidin-1-yl)-7-(3-hydroxyazetidin-1-yl)pyrazolo[1,5-a]pyrimidin-2-yl)piperidine-1-carbonyl)-4-chlorophenyl)methanesulfonamide (S)-N-(4-chloro-2-(2-(5-(3-hydroxyazetidin-1-yl)-7-(4-(2,2,2-trifluoroethyl)piperazin-1-yl)pyrazolo[1,5-a]pyrimidin-2-yl)piperidine-1-carbonyl)phenyl)methanesulfonamide (S)-N-(2-(2-(5-(azetidin-1-yl)-7-morpholinopyrazolo[1,5-a]pyrimidin-2-yl)piperidine-1-carbonyl)-4-bromophenyl)methanesulfonamide (S)-N-(2-(2-(5-(azetidin-1-yl)-7-(4-(2,2,2-trifluoroethyl)piperazin-1-yl)pyrazolo[1,5-a]pyrimidin-2-yl)piperidine-1-carbonyl)-4-chlorophenyl)methanesulfonamide (S)-N-(2-(2-(5,7-bis(3-hydroxyazetidin-1-yl)pyrazolo[1,5-a]pyrimidin-2-yl)piperidine-1-carbonyl)-4-chlorophenyl)methanesulfonamide (S)-N-(4-chloro-2-(2-(5-(3-hydroxyazetidin-1-yl)-7-(2-oxa-6-azaspiro[3.3]heptan-6-yl)pyrazolo[1,5-a]pyrimidin-2-yl)piperidine-1-carbonyl)phenyl)methanesulfonamide tert-butyl (S)-(1-(5-chloro-2-(1-(5-chloro-2-(methylsulfonamido)benzoyl)piperidin-2-yl)pyrazolo[1,5-a]pyrimidin-7-yl)azetidin-3-yl)carbamate N-(2-((2S)-2-(5-(azetidin-1-yl)-7-(3-hydroxypyrrolidin-1-yl)pyrazolo[1,5-a]pyrimidin-2-yl)piperidine-1-carbonyl)-4-chlorophenyl)methanesulfonamide (S)-N-(4-chloro-2-(2-(5,7-dichloropyrazolo[1,5-a]pyrimidin-2-yl)piperidine-1-carbonyl)phenyl)methanesulfonamide di-tert-butyl ((2-(1-(5-chloro-2-(methylsulfonamido)benzoyl)piperidin-2-yl)pyrazolo[1,5-a]pyrimidine-5,7-diyl)bis(azetidine-1,3-diyl))(S)-dicarbamate (S)-N-(2-(2-(5-(azetidin-1-yl)-7-(4-methyl-1,4-diazepan-1-yl)pyrazolo[1,5-a]pyrimidin-2-yl)piperidine-1-carbonyl)-4-chlorophenyl)methanesulfonamide (S)-N-(2-(2-(5-(azetidin-1-yl)-7-(oxazolidin-3-yl)pyrazolo[1,5-a]pyrimidin-2-yl)piperidine-1-carbonyl)-4-chlorophenyl)methanesulfonamide tert-butyl (S)-(1-(2-(1-(5-chloro-2-(methylsulfonamido)benzoyl)piperidin-2-yl)-5-(3-hydroxyazetidin-1-yl)pyrazolo[1,5-a]pyrimidin-7-yl)azetidin-3-yl)carbamate (S)-N-(2-(2-(5-(azetidin-1-yl)-7-(piperazin-1-yl)pyrazolo[1,5-a]pyrimidin-2-yl)piperidine-1-carbonyl)-4-chlorophenyl)methanesulfonamide (S)-N-(4-chloro-2-(2-(5-chloro-7-(3-hydroxy-3-methylazetidin-1-yl)pyrazolo[1,5-a]pyrimidin-2-yl)piperidine-1-carbonyl)phenyl)methanesulfonamide (S)-N-(2-(2-(7-(3-aminoazetidin-1-yl)-5-(3-hydroxyazetidin-1-yl)pyrazolo[1,5-a]pyrimidin-2-yl)piperidine-1-carbonyl)-4-chlorophenyl)methanesulfonamide hydrochloride N-(4-chloro-2-((S)-2-(5-chloro-7-((3S,5R)-3,5-dimethylpiperazin-1-yl)pyrazolo[1,5-a]pyrimidin-2-yl)piperidine-1-carbonyl)phenyl)methanesulfonamide 2,2,2-trifluoroacetate (S)-N-(2-(2-(5-(azetidin-1-yl)-7-(4-hydroxypiperidin-1-yl)pyrazolo[1,5-a]pyrimidin-2-yl)piperidine-1-carbonyl)-4-chlorophenyl)methanesulfonamide (S)-N-(4-bromo-2-(2-(5-chloro-7-morpholinopyrazolo[1,5-a]pyrimidin-2-yl)piperidine-1-carbonyl)phenyl)methanesulfonamide (S)-N-(4-chloro-2-(2-(5-chloro-7-(4-hydroxypiperidin-1-yl)pyrazolo[1,5-a]pyrimidin-2-yl)piperidine-1-carbonyl)phenyl)methanesulfonamide (S)-N-(4-bromo-2-(2-(5-(3-hydroxyazetidin-1-yl)-7-morpholinopyrazolo[1,5-a]pyrimidin-2-yl)piperidine-1-carbonyl)phenyl)methanesulfonamide (S)-N-(4-chloro-2-(2-(5-chloro-7-(4-(2,2,2-trifluoroethyl)piperazin-1-yl)pyrazolo[1,5-a]pyrimidin-2-yl)piperidine-1-carbonyl)phenyl)methanesulfonamide N-(2-((2S)-2-(7-(3-amino-4-(azetidine-1-carbonyl)pyrrolidin-1-yl)-5-(azetidin-1-yl)pyrazolo[1,5-a]pyrimidin-2-yl)piperidine-1-carbonyl)-4-chlorophenyl)methanesulfonamide