百科

利福霉素

利福霉素

CAS号：13553-79-2

英文名：Rifamycin S

分子式

C37H45NO12

熔点

179-181ºC (dec.)

密度

1.33 g/cm3

分子量

695.753

沸点

917.4ºC at 760 mmHg

溶解度

信号词

危险品标志

若想填写更详细的询价信息，请点击进入询价页面

点我

化合物简介

Semi-synthetic antibiotic.

基本信息

中文名称

利福霉素

英文名称

Rifamycin S

中文别名

利福平霉素、利福霉素-S、利福霉素S

英文别名

Rifamycin,1,4-dideoxy-1,4-dihydro-1,4-dioxo、rifamycin-S、O1,O4-didehydro-rifamycin、1,4-Dideoxy-1,4-dihydro-1,4-dioxorifamycin、rifaximin S、(12S,3E,5S,13E,15Z)-7t-acetoxy-15,9c,11t-trihydroxy-5r-methoxy-12,4,6t,8c,10c,12t,16-heptamethyl-2-oxa-18-aza-1(2,7)-naphtho[2,1-b]furana-cyclooctadecaphane-3,13,15-triene-11,6,9,17-tetraone、EINECS 236-938-4、UNII-PI53N820JV、rifomycin-S、NCI 144-130

CAS号

13553-79-2

分子式

C37H45NO12

分子量

695.753

精确质量

695.294

PSA

194.99

LOGP

3.9591

编号系统

UNII

PI53N820JV

物化性质

外观与性状

黄色橙色结晶粉末

密度

1.33 g/cm3

沸点

917.4ºC at 760 mmHg

熔点

179-181ºC (dec.)

闪点

508.6ºC

折射率

1.605

蒸汽压

0mmHg at 25°C

安全信息

海关编码

2941903000

生产方法及用途

用途

用作医药中间体。

合成路线

共找到26条合成路线 >

利福霉素B

利福霉素

上游原料

共找到3个上游原料 >

Halomicin B

二恶酮利福霉素

二恶酮利福霉素

利福霉素B

下游产品

共找到24个下游商品 >

dimethylpiperidyl benzoxazino rifamycin

dimethylpiperidyl benzoxazino rifamycin

3-cyano-rifamycin

3-cyano-rifamycin

(12S,3E,5S,13E,15Z)-7t-acetoxy-112-ethyl-15,6,9c,11t-tetrahydroxy-5r-methoxy-12,4,6t,8c,10c,12t,16-heptamethyl-2-oxa-18-aza-1(2,7)-furo[2',3':5,6]benzo[1,2-a]phenazina-cyclooctadecaphane-3,13,15-triene-11,17-dione

(12S,3E,5S,13E,15Z)-7t-acetoxy-112-ethyl-15,6,9c,11t-tetrahydroxy-5r-methoxy-12,4,6t,8c,10c,12t,16-heptamethyl-2-oxa-18-aza-1(2,7)-furo[2',3':5,6]benzo[1,2-a]phenazina-cyclooctadecaphane-3,13,15-triene-11,17-dione

8-(ethylamino)rifamycin S

8-(ethylamino)rifamycin S

(17S,3Z,5E,7S,15E)-12c-acetoxy-14,9,8c,10t-tetrahydroxy-14t-methoxy-15,7,3,7r,9t,11t,13c-heptamethyl-17-oxa-1(1,7)-furo[3',2':5,6]naphtho[1,2-d][1,2,3]triazola-cycloheptadecaphane-3,5,15-triene-18,2-dione

(17S,3Z,5E,7S,15E)-12c-acetoxy-14,9,8c,10t-tetrahydroxy-14t-methoxy-15,7,3,7r,9t,11t,13c-heptamethyl-17-oxa-1(1,7)-furo[3',2':5,6]naphtho[1,2-d][1,2,3]triazola-cycloheptadecaphane-3,5,15-triene-18,2-dione

3-((Ξ)-3-methyl-piperidin-1-yl)-O1,O4-didehydro-rifamycin

3-((Ξ)-3-methyl-piperidin-1-yl)-O1,O4-didehydro-rifamycin

上游原料

Halomicin B 二恶酮利福霉素利福霉素B

下游产品

dimethylpiperidyl benzoxazino rifamycin 3-cyano-rifamycin (12S,3E,5S,13E,15Z)-7t-acetoxy-112-ethyl-15,6,9c,11t-tetrahydroxy-5r-methoxy-12,4,6t,8c,10c,12t,16-heptamethyl-2-oxa-18-aza-1(2,7)-furo[2',3':5,6]benzo[1,2-a]phenazina-cyclooctadecaphane-3,13,15-triene-11,17-dione 8-(ethylamino)rifamycin S (17S,3Z,5E,7S,15E)-12c-acetoxy-14,9,8c,10t-tetrahydroxy-14t-methoxy-15,7,3,7r,9t,11t,13c-heptamethyl-17-oxa-1(1,7)-furo[3',2':5,6]naphtho[1,2-d][1,2,3]triazola-cycloheptadecaphane-3,5,15-triene-18,2-dione 3-((Ξ)-3-methyl-piperidin-1-yl)-O1,O4-didehydro-rifamycin (12S,17aΞ,3E,5S,13E,15Z)-7t-acetoxy-15,6,15,9c,11t-pentahydroxy-5r-methoxy-12,4,6t,8c,10c,12t,16-heptamethyl-112,13-dihydro-17aH-2-oxa-1(2,7)-furo[3'',2'':5',6']naphtho[2',3':4,5]imidazo[2,1-a]isoquinolina-cycloheptadecaphane-3,13,15-triene-11,17-dione 8-aminorifamycin S O25-deacetyl-O1,O4-didehydro-(16ξH)-16,17,18,19,28,29-hexahydro-rifamycin Rifamycin Verde 3-(4'-Phenylbutylamino)rifamycin SV 1-imino-4-oxo-1,4-dihydro-1,4-dideoxy-rifamycin 3-nitromethyl-O1,O4-didehydro-rifamycin 18,19-dihydrorifamycin S (12S,5S)-7t-acetoxy-15,9c,11t-trihydroxy-5r-methoxy-12,4,6t,8c,10c,12t,16ξ-heptamethyl-2-oxa-18-aza-1(2,7)-furo[2',3':5,6]benzo[1,2-a]phenoxazina-cyclooctadecaphan-3t-ene-11,6,17-trione 利福霉素 Q 3-((Ξ)-2-methyl-piperidin-1-yl)-O1,O4-didehydro-rifamycin 3-cyano-O1,O4-didehydro-rifamycin 3-((Ξ)-3-hydroxy-piperidin-1-yl)-O1,O4-didehydro-rifamycin 3-[4-(3-cyclohexyl-propyl)-piperidin-1-yl]-rifamycin (12S,17aΞ,3E,5S,13E,15Z)-7t-acetoxy-15,9c,11t-trihydroxy-5r-methoxy-12,4,6t,8c,10c,12t,16-heptamethyl-17a,8,9,10-tetrahydro-2-oxa-1(2,7)-furo[3',2':5,6]naphtho[2,3-d]pyrrolo[1,2-a]imidazola-cycloheptadecaphane-3,13,15-triene-11,6,12,17-dione