百科

(S)-N-(1-氮杂双环环[2.2.2]-3-辛基)-5,6,7,8-四氢-1-萘羧酰胺

CAS号：135729-78-1

英文名：N-(1-azabicyclo[2.2.2]octan-3-yl)-5,6,7,8-tetrahydronaphthalene-1-carboxamide

分子式

C18H24N2O

熔点

密度

1.17

分子量

284.396

沸点

439.2ºC at 760 mmHg

溶解度

信号词

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化合物简介

N-(3S)-1-Azabicyclo[2.2.2]oct-3-yl-5,6,7,8-tetrahydro-1-naphthalenecarboxamide is an intermediate in the synthesis of Palonosteron, an serotonin 5-HT3 receptor antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting.

基本信息

中文名称

(S)-N-(1-氮杂双环环[2.2.2]-3-辛基)-5,6,7,8-四氢-1-萘羧酰胺

英文名称

N-(1-azabicyclo[2.2.2]octan-3-yl)-5,6,7,8-tetrahydronaphthalene-1-carboxamide

中文别名

盐酸帕洛诺司琼中间体、帕洛诺司琼中间体 3、(S)-N-(1-氮杂双环[2.2.2]辛-3-基)-5,6,7,8-四氢-1-萘甲酰胺

英文别名

N-((S)-1-azabicyclo[2.2.2]oct-3-yl)-5,6,7,8-tetrahydronaphthalene-1-carboxamide、N-[(3S)-1-azabicyclo[2.2.2]oct-3-yl]-5,6,7,8-tetrahydronaphthalene-1-carboxamide、N-[(S)-1-azabicyclo[2.2.2]oct-3-yl]-5,6,7,8-tetrahydro-1-naphthalenecarboxide、1-Naphthalenecarboxamide,N-(3S)-1-azabicyclo[2.2.2]oct-3-yl-5,6,7,8-tetrahydro、N-[(S)-1-azabicyclo[2.2.2]oct-3-yl]-5,6,7,8-tetrahydro-1-naphthalenecarboxamide、(S)-N-(1-AZABICYCLO[2.2.2]OCT-3-YL)-5,6,7,8-TETRAHYDRO-1-NAPHTHALENECARBOXAMIDE

CAS号

135729-78-1

分子式

C18H24N2O

分子量

284.396

精确质量

284.189

PSA

32.34

LOGP

2.7182