化合物简介
EHop-016 is a rac GTPase inhibitor. EHop-016 is a compound that blocks the interaction of Rac with the GEF Vav in metastatic human breast cancer cells. EHop-016 also inhibits the activation of the Rac downstream effector p21-activated kinase, extension of motile actin-based structures, and cell migration.
基本信息
中文名称
EHop-016
英文名称
4-N-(9-ethylcarbazol-3-yl)-2-N-(3-morpholin-4-ylpropyl)pyrimidine-2,4-diamine
中文别名
英文别名
EHop-016、N4-(9-ethyl-9H-carbazol-3-yl)-N2-(3-morpholin-4-yl-propyl)-pyrimidine-2,4-diamine、S7319
CAS号
1380432-32-5
分子式
C25H30N6O
分子量
430.545
精确质量
430.248
PSA
73.7
LOGP
3.2639
合成路线
