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methyl N-[(10R,14S)-14-amino-10-methyl-9-oxo-16-{[2-(trimethylsilyl)ethoxy]methyl}-8,16,18-triazatricyclo[13.2.1.02,7]octadeca-1(17),2,4,6,15(18)-pentaen-5-yl]carbamate

methyl N-[(10R,14S)-14-amino-10-methyl-9-oxo-16-{[2-(trimethylsilyl)ethoxy]methyl}-8,16,18-triazatricyclo[13.2.1.02,7]octadeca-1(17),2,4,6,15(18)-pentaen-5-yl]carbamate

CAS号：1422387-44-7

英文名：methyl N-[(10R,14S)-14-amino-10-methyl-9-oxo-16-{[2-(trimethylsilyl)ethoxy]methyl}-8,16,18-triazatricyclo[13.2.1.02,7]octadeca-1(17),2,4,6,15(18)-pentaen-5-yl]carbamate

分子式

C24H37N5O4Si

熔点

密度

分子量

487.667

沸点

溶解度

信号词

危险品标志

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基本信息

中文名称

methyl N-[(10R,14S)-14-amino-10-methyl-9-oxo-16-{[2-(trimethylsilyl)ethoxy]methyl}-8,16,18-triazatricyclo[13.2.1.02,7]octadeca-1(17),2,4,6,15(18)-pentaen-5-yl]carbamate

英文名称

methyl N-[(10R,14S)-14-amino-10-methyl-9-oxo-16-{[2-(trimethylsilyl)ethoxy]methyl}-8,16,18-triazatricyclo[13.2.1.02,7]octadeca-1(17),2,4,6,15(18)-pentaen-5-yl]carbamate

中文别名

英文别名

methyl N-((3R,7S)-7-amino-3-methyl-2-oxo-9-((2-(trimethylsilyl)ethoxy)methyl)-1,2,3,4,5,6,7,9-octahydro-11,8-(azeno)-1,9-benzodiazacyclotridecin-14-yl)carbamate

CAS号

1422387-44-7

分子式

C24H37N5O4Si

分子量

487.667

精确质量

487.261

PSA

120.5

LOGP

5.7103

合成路线

共找到6条合成路线 >

{3-bromo-4-[2-((S)-1-tert-butoxycarbonylaminobut-3-enyl)-3H-imidazol-4-yl]phenyl}carbamic acid methyl ester

{3-bromo-4-[2-((S)-1-tert-butoxycarbonylaminobut-3-enyl)-3H-imidazol-4-yl]phenyl}carbamic acid methyl ester

methyl N-[(10R,14S)-14-amino-10-methyl-9-oxo-16-{[2-(trimethylsilyl)ethoxy]methyl}-8,16,18-triazatricyclo[13.2.1.02,7]octadeca-1(17),2,4,6,15(18)-pentaen-5-yl]carbamate

methyl N-[(10R,14S)-14-amino-10-methyl-9-oxo-16-{[2-(trimethylsilyl)ethoxy]methyl}-8,16,18-triazatricyclo[13.2.1.02,7]octadeca-1(17),2,4,6,15(18)-pentaen-5-yl]carbamate

上游原料

共找到3个上游原料 >

tert-butyl N-[(1S)-1-(4-{2-bromo-4-[(methoxycarbonyl)-amino]phenyl}-1-{[2-(trimethylsilyl)ethoxy]methyl}-1H-imidazol-2-yl)but-3-en-1-yl]carbamate

tert-butyl N-[(1S)-1-(4-{2-bromo-4-[(methoxycarbonyl)-amino]phenyl}-1-{[2-(trimethylsilyl)ethoxy]methyl}-1H-imidazol-2-yl)but-3-en-1-yl]carbamate

{3-bromo-4-[2-((S)-1-tert-butoxycarbonylaminobut-3-enyl)-3H-imidazol-4-yl]phenyl}carbamic acid methyl ester

{3-bromo-4-[2-((S)-1-tert-butoxycarbonylaminobut-3-enyl)-3H-imidazol-4-yl]phenyl}carbamic acid methyl ester

tert-butyl N-[(10R,11E,14S)-5-[(methoxycarbonyl)amino]-10-methyl-9-oxo-16-{[2-(trimethylsilyl)ethoxy]methyl}-8,16,18-triazatricyclo[13.2.1.02'7]octadeca-1(17),2,4,6,11,15(18)-hexaen-14-yl]carbamate

tert-butyl N-[(10R,11E,14S)-5-[(methoxycarbonyl)amino]-10-methyl-9-oxo-16-{[2-(trimethylsilyl)ethoxy]methyl}-8,16,18-triazatricyclo[13.2.1.02'7]octadeca-1(17),2,4,6,11,15(18)-hexaen-14-yl]carbamate

下游产品

共找到6个下游商品 >

methyl N-[(10R,14S)-14-[6-(2-fluoro-3-methoxyphenyl)-2-oxo-1,3-oxazinan-3-yl]-10-methyl-9-oxo-8,16,18-triazatricyclo[13.2.1.02,7]octadeca-1(17),2,4,6,15(18)-pentaen-5-yl]carbamate trifluoroacetate

methyl N-[(10R,14S)-14-[6-(2-fluoro-3-methoxyphenyl)-2-oxo-1,3-oxazinan-3-yl]-10-methyl-9-oxo-8,16,18-triazatricyclo[13.2.1.02,7]octadeca-1(17),2,4,6,15(18)-pentaen-5-yl]carbamate trifluoroacetate

methyl N-[(10R,14S)-14-[(6R)-6-(3-chloro-2,6-difluorophenyl)-2-oxo-1,3-oxazinan-3-yl]-10-methyl-9-oxo-8,16,18-triazatricyclo[13.2.1.02,7]octadeca-1(17),2,4,6,15(18)-pentaen-5-yl]carbamate

methyl N-[(10R,14S)-14-[(6R)-6-(3-chloro-2,6-difluorophenyl)-2-oxo-1,3-oxazinan-3-yl]-10-methyl-9-oxo-8,16,18-triazatricyclo[13.2.1.02,7]octadeca-1(17),2,4,6,15(18)-pentaen-5-yl]carbamate

methyl N-[(10R,14S)-14-[6-(3-chloro-2,6-difluorophenyl)-2-oxo-1,3-oxazinan-3-yl]-10-methyl-9-oxo-16-{[2-(trimethylsilyl)ethoxy]methyl}-8,16,18-triazatricyclo[13.2.1.02,7]octadeca-1(17),2,4,6,15(18)-pentaen-5-yl]carbamate

methyl N-[(10R,14S)-14-[6-(3-chloro-2,6-difluorophenyl)-2-oxo-1,3-oxazinan-3-yl]-10-methyl-9-oxo-16-{[2-(trimethylsilyl)ethoxy]methyl}-8,16,18-triazatricyclo[13.2.1.02,7]octadeca-1(17),2,4,6,15(18)-pentaen-5-yl]carbamate

methyl N-[(10R,14S)-14-[6-(2-fluoro-3-methoxyphenyl)-2-oxo-1,3-oxazinan-3-yl]-10-methyl-9-oxo-16-{[2-(trimethylsilyl)ethoxy]methyl}-8,16,18-triazatricyclo[13.2.1.02,7]octadeca-1(17),2,4,6,15(18)-pentaen-5-yl]carbamate

methyl N-[(10R,14S)-14-[6-(2-fluoro-3-methoxyphenyl)-2-oxo-1,3-oxazinan-3-yl]-10-methyl-9-oxo-16-{[2-(trimethylsilyl)ethoxy]methyl}-8,16,18-triazatricyclo[13.2.1.02,7]octadeca-1(17),2,4,6,15(18)-pentaen-5-yl]carbamate

methyl N-[(10R,14S)-14-{[3-(3-chloro-2,6-difluorophenyl)-3-hydroxypropyl]amino}-10-methyl-9-oxo-16-{[2-(trimethylsilyl)ethoxy]methyl}-8,16,18-triazatricyclo[13.2.1.02,7]octadeca-1(17),2,4,6,15(18)-pentaen-5-yl]carbamate

methyl N-[(10R,14S)-14-{[3-(3-chloro-2,6-difluorophenyl)-3-hydroxypropyl]amino}-10-methyl-9-oxo-16-{[2-(trimethylsilyl)ethoxy]methyl}-8,16,18-triazatricyclo[13.2.1.02,7]octadeca-1(17),2,4,6,15(18)-pentaen-5-yl]carbamate

phenyl ((R)-3-((tert-butyldimethylsilyl)oxy)-3-(4-chloro-3-fluoropyridin-2-yl)propyl)((5R,9S,Z)-24-((methoxycarbonyl)amino)-5-methyl-4-oxo-11-((2-(trimethylsilyl)ethoxy)methyl)-11H-3-aza-1(4,2)-imidazola-2(1,2)-benzenacyclononaphane-9-yl)carbamate

phenyl ((R)-3-((tert-butyldimethylsilyl)oxy)-3-(4-chloro-3-fluoropyridin-2-yl)propyl)((5R,9S,Z)-24-((methoxycarbonyl)amino)-5-methyl-4-oxo-11-((2-(trimethylsilyl)ethoxy)methyl)-11H-3-aza-1(4,2)-imidazola-2(1,2)-benzenacyclononaphane-9-yl)carbamate

上游原料

tert-butyl N-[(1S)-1-(4-{2-bromo-4-[(methoxycarbonyl)-amino]phenyl}-1-{[2-(trimethylsilyl)ethoxy]methyl}-1H-imidazol-2-yl)but-3-en-1-yl]carbamate {3-bromo-4-[2-((S)-1-tert-butoxycarbonylaminobut-3-enyl)-3H-imidazol-4-yl]phenyl}carbamic acid methyl ester tert-butyl N-[(10R,11E,14S)-5-[(methoxycarbonyl)amino]-10-methyl-9-oxo-16-{[2-(trimethylsilyl)ethoxy]methyl}-8,16,18-triazatricyclo[13.2.1.02'7]octadeca-1(17),2,4,6,11,15(18)-hexaen-14-yl]carbamate

下游产品

methyl N-[(10R,14S)-14-[6-(2-fluoro-3-methoxyphenyl)-2-oxo-1,3-oxazinan-3-yl]-10-methyl-9-oxo-8,16,18-triazatricyclo[13.2.1.02,7]octadeca-1(17),2,4,6,15(18)-pentaen-5-yl]carbamate trifluoroacetate methyl N-[(10R,14S)-14-[(6R)-6-(3-chloro-2,6-difluorophenyl)-2-oxo-1,3-oxazinan-3-yl]-10-methyl-9-oxo-8,16,18-triazatricyclo[13.2.1.02,7]octadeca-1(17),2,4,6,15(18)-pentaen-5-yl]carbamate methyl N-[(10R,14S)-14-[6-(3-chloro-2,6-difluorophenyl)-2-oxo-1,3-oxazinan-3-yl]-10-methyl-9-oxo-16-{[2-(trimethylsilyl)ethoxy]methyl}-8,16,18-triazatricyclo[13.2.1.02,7]octadeca-1(17),2,4,6,15(18)-pentaen-5-yl]carbamate methyl N-[(10R,14S)-14-[6-(2-fluoro-3-methoxyphenyl)-2-oxo-1,3-oxazinan-3-yl]-10-methyl-9-oxo-16-{[2-(trimethylsilyl)ethoxy]methyl}-8,16,18-triazatricyclo[13.2.1.02,7]octadeca-1(17),2,4,6,15(18)-pentaen-5-yl]carbamate methyl N-[(10R,14S)-14-{[3-(3-chloro-2,6-difluorophenyl)-3-hydroxypropyl]amino}-10-methyl-9-oxo-16-{[2-(trimethylsilyl)ethoxy]methyl}-8,16,18-triazatricyclo[13.2.1.02,7]octadeca-1(17),2,4,6,15(18)-pentaen-5-yl]carbamate phenyl ((R)-3-((tert-butyldimethylsilyl)oxy)-3-(4-chloro-3-fluoropyridin-2-yl)propyl)((5R,9S,Z)-24-((methoxycarbonyl)amino)-5-methyl-4-oxo-11-((2-(trimethylsilyl)ethoxy)methyl)-11H-3-aza-1(4,2)-imidazola-2(1,2)-benzenacyclononaphane-9-yl)carbamate