化合物简介
Landiolol is an ultra-short acting beta blocker that is used to treat patients with cardiac arrhythmias and is also used to treat tachycardia during anasthesia.
基本信息
中文名称
[(4S)-2,2-二甲基-1,3-二氧戊环-4-基]甲基 3-[4-[(2S)-2-羟基-3-[2-(吗啉-4-甲酰氨基)乙基氨基]丙氧基]苯基]丙酸酯盐酸盐
英文名称
Landiolol hydrochloride
中文别名
盐酸兰地洛尔
英文别名
Ono 1101 hydrochloride、(-)-[(S)-2,2-dimethyl-1,3-dioxolan-4-yl]methyl-3-[4-[(S)-2-hydroxy-3-(2-morpholinocarbonylamino)ethylamino]propoxy]phenylpropionic acid hydrochloride、((S)-2,2-dimethyl-1,3-dioxolan-4-yl)methyl 3-(4-((S)-2-hydroxy-3-(2-(morpholine-4-carboxamido)ethylamino)propoxy)phenyl)propanoate hydrochloride、2,2-dimethyl-1,3-dioxolan-4S-yl-methyl 3-[P-{3-{(2-(morpholinocarbonylamino)ethyl)amino}-2S-hydroxypropoxy}phenyl] propionate hydrochloride、[(4S)-2,2-dimethyl-1,3-dioxolan-4-yl]methyl 3-[4-[(2S)-2-hydroxy-3-[2-(morpholine-4-carbonylamino)ethylamino]propoxy]phenyl]propanoate hydrochloride、Benzenepropanoic acid,4-(2-hydroxy-3-((2-((4-morpholinylcarbonyl)amino)ethyl)amino)propoxy)-,(2,2-dimethyl-1,3-dioxolan-4-yl)methyl ester,(S-(R*,R*))-,hydrochloride、Landiololhydrochloride、(-)-[(S)-2,2-dimethyl-1,3-dioxolan-4-yl]methyl 3-[4-[(S)-2-hydroxy-3-(2-(morpholinocarbonylamino)ethylamino)propoxy]phenyl]propionate monohydrochloride
CAS号
144481-98-1
分子式
C25H40ClN3O8
分子量
546.053
精确质量
545.25
PSA
127.82
LOGP
2.3776
编号系统
UNII
G8HQ634Y17
物化性质
外观与性状
白色结晶粉末
密度
1.201g/cm3
沸点
727.5ºC at 760mmHg
熔点
122-127ºC
闪点
393.8ºC
蒸汽压
3.24E-22mmHg at 25°C
合成路线
