百科

2-(((2R,3S,4R,5R)-3-(benzyloxy)-5-(3-((benzyloxy)methyl)-5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-hydroxytetrahydrofuran-2-yl)oxy)ethyl 4-methylbenzenesulfonate

CAS号：1446748-44-2

英文名：2-(((2R,3S,4R,5R)-3-(benzyloxy)-5-(3-((benzyloxy)methyl)-5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-hydroxytetrahydrofuran-2-yl)oxy)ethyl 4-methylbenzenesulfonate

分子式：C55H56N2O13S

分子量：985.104

合成路线

1446748-41-9

1-((2R,3R,4S,5R)-4-(benzyloxy)-5-(2-((tert-butyldimethylsilyl)oxy)ethoxy)-3-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-3-((benzyloxy)methyl)-5-methylpyrimidine-2,4(1H,3H)-dione

1446748-44-2

2-(((2R,3S,4R,5R)-3-(benzyloxy)-5-(3-((benzyloxy)methyl)-5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-hydroxytetrahydrofuran-2-yl)oxy)ethyl 4-methylbenzenesulfonate

239808-67-4

4,4'-dimethoxytrityl trifluoromethanesulfonate

1446748-44-2

1446748-42-0

1-((2R,3R,4S,5R)-4-(benzyloxy)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(2-((tert-butyldimethylsilyl)oxy)ethoxy)-3-hydroxytetrahydrofuran-2-yl)-3-((benzyloxy)methyl)-5-methylpyrimidine-2,4(1H,3H)-dione

1446748-44-2

1446748-34-0

3-((benzyloxy)methyl)-1-((2R,3R,4S)-3,4-dihydroxy-5-methylenetetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione

1446748-44-2

1446748-36-2

1-((2R,3R,4S)-4-(benzyloxy)-3-hydroxy-5-methylenetetrahydrofuran-2-yl)-3-((benzyloxy)methyl)-5-methylpyrimidine-2,4(1H,3H)-dione

1446748-44-2

上游原料

1-((2R,3R,4S,5R)-4-(benzyloxy)-5-(2-((tert-butyldimethylsilyl)oxy)ethoxy)-3-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-3-((benzyloxy)methyl)-5-methylpyrimidine-2,4(1H,3H)-dione 4,4'-dimethoxytrityl trifluoromethanesulfonate 1-((2R,3R,4S)-4-(benzyloxy)-3-hydroxy-5-methylenetetrahydrofuran-2-yl)-3-((benzyloxy)methyl)-5-methylpyrimidine-2,4(1H,3H)-dione 1-((2R,3R,4S,5R)-4-(benzyloxy)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(2-((tert-butyldimethylsilyl)oxy)ethoxy)-3-hydroxytetrahydrofuran-2-yl)-3-((benzyloxy)methyl)-5-methylpyrimidine-2,4(1H,3H)-dione 3-((benzyloxy)methyl)-1-((2R,3R,4S)-3,4-dihydroxy-5-methylenetetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione

下游产品

(1R,6R,8R,9S)-6-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-8-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-2,5,7-trioxabicyclo[4.2.1]nonan-9-yl (2-cyanoethyl) diisopropylphosphoramidite 1-((1R,6R,8R,9S)-6-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-9-hydroxy-2,5,7-trioxabicyclo[4.2.1]nonan-8-yl)-5-methylpyrimidine-2,4(1H,3H)-dione 2'-O,4'-C-ethyleneoxy-5-methyluridine 1-((1R,6R,8R,9S)-9-(benzyloxy)-6-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-2,5,7-trioxabicyclo[4.2.1]nonan-8-yl)-3-((benzyloxy)methyl)-5-methylpyrimidine-2,4(1H,3H)-dione