化合物简介
Resiquimod (R-848) is a drug that acts as an immune response modifier, and has antiviral and antitumour activity. It is used as a topical gel in the treatment of skin lesions such as those caused by the herpes simplex virus and cutaneous T cell lymphoma, and as an adjuvant to increase the effectiveness of vaccines. It has several mechanisms of action, being both an agonist for toll-like receptor 7 and 8, and an upregulator of the opioid growth factor receptor.
基本信息
中文名称
雷西莫特
英文名称
resiquimod
中文别名
4-氨基-2-乙氧基甲基-ALPHA,ALPHA-二甲基-1H-咪唑并[4,5-C]喹啉-1-乙醇、1-(4-氨基-2-(乙氧基甲基)-1H-咪唑并[4,5-C]喹啉-1-基)-2-甲基-2-丙醇
英文别名
1-[4-amino-2-(ethoxymethyl)imidazo[4,5-c]quinolin-1-yl]-2-methylpropan-2-ol、1-(4-Amino-2-(ethoxymethyl)-1H-imidazo[4,5-c]quinolin-1-yl)-2-methylpropan-2-ol
CAS号
144875-48-9
分子式
C17H22N4O2
分子量
314.382
精确质量
314.174
PSA
86.19
LOGP
3.0553
编号系统
MDL号
MFCD00937759
物化性质
密度
1.28g/cm3
沸点
553.6ºC at 760mmHg
闪点
288.6ºC
折射率
1.634
蒸汽压
4.33E-13mmHg at 25°C
安全信息
海关编码
2933990090
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