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(1S,2R)-1-((2S,5R)-5-(((6,7-dihydro-[1,4]dioxino[2,3-c]pyridazin-3-yl)methyl)amino)tetrahydro-2H-pyran-2-yl)-2-(3-fluoro-6-methoxy-1,5-naphthyridin-4-yl)ethane-1,2-diol

(1S,2R)-1-((2S,5R)-5-(((6,7-dihydro-[1,4]dioxino[2,3-c]pyridazin-3-yl)methyl)amino)tetrahydro-2H-pyran-2-yl)-2-(3-fluoro-6-methoxy-1,5-naphthyridin-4-yl)ethane-1,2-diol

CAS号：1455011-06-9

英文名：(1S,2R)-1-((2S,5R)-5-(((6,7-dihydro-[1,4]dioxino[2,3-c]pyridazin-3-yl)methyl)amino)tetrahydro-2H-pyran-2-yl)-2-(3-fluoro-6-methoxy-1,5-naphthyridin-4-yl)ethane-1,2-diol

分子式

C23H26FN5O6

熔点

密度

分子量

487.481

沸点

溶解度

信号词

危险品标志

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基本信息

中文名称

(1S,2R)-1-((2S,5R)-5-(((6,7-dihydro-[1,4]dioxino[2,3-c]pyridazin-3-yl)methyl)amino)tetrahydro-2H-pyran-2-yl)-2-(3-fluoro-6-methoxy-1,5-naphthyridin-4-yl)ethane-1,2-diol

英文名称

(1S,2R)-1-((2S,5R)-5-(((6,7-dihydro-[1,4]dioxino[2,3-c]pyridazin-3-yl)methyl)amino)tetrahydro-2H-pyran-2-yl)-2-(3-fluoro-6-methoxy-1,5-naphthyridin-4-yl)ethane-1,2-diol

中文别名

英文别名

CAS号

1455011-06-9

分子式

C23H26FN5O6

分子量

487.481

精确质量

487.187

PSA

140.97

LOGP

1.4613

合成路线

tert-butyl ((3R,6S)-6-((E)-2-(3-fluoro-6-methoxy-1,5-naphthyridin-4-yl)vinyl)tetrahydro-2H-pyran-3-yl)carbamate

tert-butyl ((3R,6S)-6-((E)-2-(3-fluoro-6-methoxy-1,5-naphthyridin-4-yl)vinyl)tetrahydro-2H-pyran-3-yl)carbamate

(1S,2R)-1-((2S,5R)-5-(((6,7-dihydro-[1,4]dioxino[2,3-c]pyridazin-3-yl)methyl)amino)tetrahydro-2H-pyran-2-yl)-2-(3-fluoro-6-methoxy-1,5-naphthyridin-4-yl)ethane-1,2-diol

(1S,2R)-1-((2S,5R)-5-(((6,7-dihydro-[1,4]dioxino[2,3-c]pyridazin-3-yl)methyl)amino)tetrahydro-2H-pyran-2-yl)-2-(3-fluoro-6-methoxy-1,5-naphthyridin-4-yl)ethane-1,2-diol

上游原料

共找到9个上游原料 >

(1S,2R)-1-[(2S,5R)-5-aminooxan-2-yl]-2-(3-fluoro-6-methoxy-1,5-naphthyridin-4-yl)ethane-1,2-diol

(1S,2R)-1-[(2S,5R)-5-aminooxan-2-yl]-2-(3-fluoro-6-methoxy-1,5-naphthyridin-4-yl)ethane-1,2-diol

toluene-4-sulfonic acid (2S,5R)-5-tert-butoxycarbonylamino-tetrahydro-pyran-2-ylmethyl ester

toluene-4-sulfonic acid (2S,5R)-5-tert-butoxycarbonylamino-tetrahydro-pyran-2-ylmethyl ester

3-fluoro-6-methoxy-[1,5]naphthyridine-4-carbaldehyde

3-fluoro-6-methoxy-[1,5]naphthyridine-4-carbaldehyde

tert-butyl ((3R,6S)-6-((E)-2-(3-fluoro-6-methoxy-1,5-naphthyridin-4-yl)vinyl)tetrahydro-2H-pyran-3-yl)carbamate

tert-butyl ((3R,6S)-6-((E)-2-(3-fluoro-6-methoxy-1,5-naphthyridin-4-yl)vinyl)tetrahydro-2H-pyran-3-yl)carbamate

6H,7H-[1,4]dioxino[2,3-c]pyridazine-3-carbaldehyde

6H,7H-[1,4]dioxino[2,3-c]pyridazine-3-carbaldehyde

tert-butyl ((3R,6S)-6-(((1-phenyl-1H-tetrazol-5-yl)thio)methyl)-tetrahydro-2H-pyran-3-yl)carbamate

tert-butyl ((3R,6S)-6-(((1-phenyl-1H-tetrazol-5-yl)thio)methyl)-tetrahydro-2H-pyran-3-yl)carbamate

上游原料

(1S,2R)-1-[(2S,5R)-5-aminooxan-2-yl]-2-(3-fluoro-6-methoxy-1,5-naphthyridin-4-yl)ethane-1,2-diol toluene-4-sulfonic acid (2S,5R)-5-tert-butoxycarbonylamino-tetrahydro-pyran-2-ylmethyl ester 3-fluoro-6-methoxy-[1,5]naphthyridine-4-carbaldehyde tert-butyl ((3R,6S)-6-((E)-2-(3-fluoro-6-methoxy-1,5-naphthyridin-4-yl)vinyl)tetrahydro-2H-pyran-3-yl)carbamate 6H,7H-[1,4]dioxino[2,3-c]pyridazine-3-carbaldehyde tert-butyl ((3R,6S)-6-(((1-phenyl-1H-tetrazol-5-yl)thio)methyl)-tetrahydro-2H-pyran-3-yl)carbamate (E)-7-fluoro-2-methoxy-8-styryl-1,5-naphthyridine tert-butyl ((3R,6S)-6-(iodomethyl)tetrahydro-2H-pyran-3-yl)carbamate 1-(3-fluoro-6-methoxy-1,5-naphthyridin-4-yl)-2-phenylethane-1,2-diol