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FR901464

FR901464

CAS号：146478-72-0

英文名：FR901464

分子式

C27H41NO8

熔点

密度

1.21g/cm3

分子量

507.616

沸点

702.7ºC at 760mmHg

溶解度

信号词

危险品标志

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基本信息

中文名称

FR901464

英文名称

FR901464

中文别名

英文别名

[(E,2S)-5-[[(2R,5S,6S)-6-[(2E,4E)-5-[(4R,5R,7S)-4,7-dihydroxy-7-methyl-1,6-dioxaspiro[2.5]octan-5-yl]-3-methylpenta-2,4-dienyl]-2,5-dimethyloxan-3-yl]amino]-5-oxopent-3-en-2-yl] acetate、[(E,2S)-5-[[(2R,5S,6S)-6-[(2E,4E)-5-[(5S,7R,8R)-5,8-dihydroxy-5-methyl-2,6-dioxaspiro[2.5]octan-7-yl]-3-methylpenta-2,4-dienyl]-2,5-dimethyloxan-3-yl]amino]-5-oxopent-3-en-2-yl] acetate、WB 2663B

CAS号

146478-72-0

分子式

C27H41NO8

分子量

507.616

精确质量

507.283

PSA

130.34

LOGP

3.1527

物化性质

密度

1.21g/cm3

沸点

702.7ºC at 760mmHg

闪点

378.8ºC

折射率

1.553

蒸汽压

7.94E-23mmHg at 25°C

合成路线

共找到1条合成路线 >

spliceostatin A

spliceostatin A

FR901464

上游原料

共找到55个上游原料 >

(2R,3S,6S)-(3-hydroxy-6-methoxy-6-methyl-4-methylenetetrahydropyran-2-yl)methyl pivalate

(2R,3S,6S)-(3-hydroxy-6-methoxy-6-methyl-4-methylenetetrahydropyran-2-yl)methyl pivalate

(3R)-azido-(6S)-(3-iodo-but-(2E)-enyl)-(2R,5S)-dimethyl-tetrahydropyran

(3R)-azido-(6S)-(3-iodo-but-(2E)-enyl)-(2R,5S)-dimethyl-tetrahydropyran

tert-butyl ((2R,3R)-2,5-dimethyl-3,6-dihydro-2H-pyran-3-yl)carbamate

tert-butyl ((2R,3R)-2,5-dimethyl-3,6-dihydro-2H-pyran-3-yl)carbamate

(S,Z)-N-((2R,3R,5S,6S)-6-((2E,4E)-5-((3R,4R,5R,7S)-4-((tert-butyldimethylsilyl)oxy)-7-methoxy-7-methyl-1,6-dioxaspiro[2.5]octan-5-yl)-3-methylpenta-2,4-dien-1-yl)-2,5-dimethyltetrahydro-2H-pyran-3-yl)-4-hydroxypent-2-enamide

(S,Z)-N-((2R,3R,5S,6S)-6-((2E,4E)-5-((3R,4R,5R,7S)-4-((tert-butyldimethylsilyl)oxy)-7-methoxy-7-methyl-1,6-dioxaspiro[2.5]octan-5-yl)-3-methylpenta-2,4-dien-1-yl)-2,5-dimethyltetrahydro-2H-pyran-3-yl)-4-hydroxypent-2-enamide

(6S)-(3-iodo-but-(2E)-enyl)-(2R,5S)-dimethyl-tetrahydropyran-(3S)-ol

(6S)-(3-iodo-but-(2E)-enyl)-(2R,5S)-dimethyl-tetrahydropyran-(3S)-ol

(4S)-acetoxy-pent-2-ynoic acid

(4S)-acetoxy-pent-2-ynoic acid

下游产品

共找到1个下游商品 >

spliceostatin A

spliceostatin A

上游原料

(2R,3S,6S)-(3-hydroxy-6-methoxy-6-methyl-4-methylenetetrahydropyran-2-yl)methyl pivalate (3R)-azido-(6S)-(3-iodo-but-(2E)-enyl)-(2R,5S)-dimethyl-tetrahydropyran tert-butyl ((2R,3R)-2,5-dimethyl-3,6-dihydro-2H-pyran-3-yl)carbamate (S,Z)-N-((2R,3R,5S,6S)-6-((2E,4E)-5-((3R,4R,5R,7S)-4-((tert-butyldimethylsilyl)oxy)-7-methoxy-7-methyl-1,6-dioxaspiro[2.5]octan-5-yl)-3-methylpenta-2,4-dien-1-yl)-2,5-dimethyltetrahydro-2H-pyran-3-yl)-4-hydroxypent-2-enamide (6S)-(3-iodo-but-(2E)-enyl)-(2R,5S)-dimethyl-tetrahydropyran-(3S)-ol (4S)-acetoxy-pent-2-ynoic acid (2Z,4E)-3-triethylsilyloxy-2,4-hexadiene (6S)-but-3-ynyl-(2R,5S)-dimethyl-tetrahydropyran-(3S)-ol (1S,4S,6R,9R)-4-methoxy-9-(4'-methoxyphenyl)-4-methyl-5,8,10-trioxabicyclo[4.4.0]decan-2-one Acetic acid (Z)-(S)-3-{(2R,3R,5S,6S)-6-[(2E,4E)-5-((3R,4R,5R)-4-hydroxy-7-methylene-1,6-dioxa-spiro[2.5]oct-5-yl)-3-methyl-penta-2,4-dienyl]-2,5-dimethyl-tetrahydro-pyran-3-ylcarbamoyl}-1-methyl-allyl ester (-)-(S)-4-hydroxypent-2-ynoic acid (((3R,4R,5R,7R)-5-((1E,3E)-5-((2S,3S,5R,6R)-5-azido-3,6-dimethyltetrahydro-2H-pyran-2-yl)-3-methylpenta-1,3-dien-1-yl)-7-(iodomethyl)-1,6-dioxaspiro[2.5]octan-4-yl)oxy)triethylsilane (1S,2R,4S,6R,9R)-4-methoxy-9-(4'-methoxyphenyl)-4-methyl-5,8,10-trioxabicyclo[4.4.0]decan-2-ol spliceostatin A (3R,4R,5R,7S)-(4-t-butyldimethylsilyloxy-7-methoxy-7-methyl-1,6-dioxaspiro[2.5]oct-5-yl)methanol (3R,4R,5R,7S)-7-methyl-5-vinyl-1,6-dioxaspiro[2.5]octane-4,7-diol (2'E,2''S,3''S,5''R,6''R)-2-{[4'-(5''-amino-3'',6''-dimethyltetrahydropyran-2''-yl)-2'-methylbut-2'-en-1'-yl]sulfonyl}-1,3-benzothiazole methyl (2S,3S,5R,6R)-(5-t-butoxycarbonylamino-3,6-dimethyltetrahydropyran-2-yl)acetate (S)-4-formylbut-3-yn-2-yl acetate (2R,3R,5S,6S)-6-allyl-2,5-dimethyltetrahydro-2H-pyran-3-amine (Z)-(4S)-4-acetoxypent-2-enoic acid tert-butyl ((3R,4R)-4-hydroxypent-1-en-3-yl)carbamate (4R)-triethylsilyloxy-(5R)-ethynyl-(7R)-iodomethyl-1,6-dioxa-spiro[2,5]octane (2'E,2''S,3''S,5''R,6''R)-4-{[4'-(5''-t-butoxycarbonylamino-3'',6''-dimethyltetrahydropyran-2''-yl)-2'-methylbut-2'-en-1'-yl]sulfanyl}-1,3-benzothiazole ((2R,3R)-2,5-Dimethyl-6-oxo-3,6-dihydro-2H-pyran-3-yl)-carbamic acid tert-butyl ester (S,Z)-5-(((2R,3R,5S,6S)-6-((2E,4E)-5-((3R,4R,5R,7S)-4-((tert-butyldimethylsilyl)oxy)-7-methoxy-7-methyl-1,6-dioxaspiro[2.5]octan-5-yl)-3-methylpenta-2,4-dien-1-yl)-2,5-dimethyltetrahydro-2H-pyran-3-yl)amino)-5-oxopent-3-en-2-yl acetate (3R,6R)-dimethyl-4-(triethylsilanyloxy)-(2S)-[4-(trimethylsilanyl)-but-3-ynyl]-3,6-dihydro-2H-pyran (S,Z)-4-((tert-butyldimethylsilyl)oxy)-N-((2R,3R,5S,6S)-6-((2E,4E)-5-((3R,4R,5R,7S)-4-((tert-butyldimethylsilyl)oxy)-7-methoxy-7-methyl-1,6-dioxaspiro[2.5]octan-5-yl)-3-methylpenta-2,4-dien-1-yl)-2,5-dimethyltetrahydro-2H-pyran-3-yl)pent-2-enamide (3R)-hydroxy-(2R,5R)-dimethyl-(6S)-[4-(trimethylsilanyl)-but-3-ynyl]-tetrahydropyran-4-one (3R,4R,5R,7S)-(4-hydroxy-7-methoxy-7-methyl-1,6-dioxaspiro[2.5]oct-5-yl)methyl pivalate (2Z,2'R,2''E,3'R,4S,5'S,6'S)-N-{6'-[4''-(1''',3'''-benzothiazol-2'''-ylsulfonyl)-3''-methylbut-2''-en-1''-yl]-2',5'-dimethyltetrahydropyran-3'-yl}-4-t-butyldimethylsilyloxypent-2-enamide tert-butyl ((2R,3R,5S,6S)-6-allyl-2,5-dimethyltetrahydro-2H-pyran-3-yl)carbamate (6S)-butynyl-(2R,5S)-dimethyl-tetrahydropyran-(3S)-ol methyl (R,E)-4-hydroxy-4-((R)-2-(2-methylallyl)oxiran-2-yl)but-2-enoate (2R,5S)-dimethyl-(6S)-[4-(trimethylsilanyl)-but-3-ynyl]-tetrahydropyran-(3S)-ol (3R,4R,5S,7S)-4-t-butyldimethylsilyloxy-7-methoxy-7-methyl-1,6-dioxaspiro[2.5]octane-5-carbaldehyde (1S,3R,6R,9S)-8-methoxy-3-(4'-methoxyphenyl)-8-methyl-10-methylene-2,4,7-trioxabicyclo[4.4.0]decane (S,Z)-4-((TBS)oxy)pent-2-enoic acid (2S,3S,5R,6R)-(5-t-butoxycarbonylamino-3,6-dimethyltetrahydropyran-2-yl)acetaldehyde (1R,2R)-1-[(R)-2-(2-Methyl-allyl)-oxiranyl]-1-triethylsilanyloxy-but-3-en-2-ol (3R,4R,5R,7S)-(4-t-butyldimethylsilyloxy-7-methoxy-7-methyl-1,6-dioxaspiro[2.5]oct-5-yl)methyl pivalate (S,Z)-5-((2R,3R,5S,6S)-2,5-dimethyl-6-((E)-3- methylpenta-2,4-dienyl)-tetrahydro-2H-pyran-3-ylamino)-5-oxopent-3-en-2-yl acetate 5-trimethylsilylpent-4-ynal (S,Z)-5-(((2R,3R,5S,6S)-6-((2E,4E)-5-((3R,4R,5R,7R)-7-(iodomethyl)-4-((triethylsilyl)oxy)-1,6-dioxaspiro[2.5]octan-5-yl)-3-methylpenta-2,4-dien-1-yl)-2,5-dimethyltetrahydro-2H-pyran-3-yl)amino)-5-oxopent-3-en-2-yl acetate methyl (2R,3R)-(3-t-butoxycarbonylamino-2,5-dimethyl-3,4-dihydro-2H-pyran-6-yl)acetate (2'E,2''S,3''S,5''R,6''R)-2-{[4'-(5''-t-butoxycarbonylamino-3'',6''-dimethyltetrahydropyran-2''-yl)-2'-methylbut-2'-en-1'-yl]sulfonyl}-1,3-benzothiazole tert-butyl (4R,5R)-2,2,5-trimethyl-4-vinyloxazolidine-3-carboxylate (E)-(2S)-6-phenylhex-5-en-3-yn-2-yl acetate (Z)-(S)-4-(tert-butyldimethylsilanyloxy)pent-2-enoic acid methyl ester

下游产品

spliceostatin A