百科

沙普立沙坦

CAS号：146623-69-0

英文名：3-[[3-bromo-2-[2-(trifluoromethylsulfonylamino)phenyl]-1-benzofuran-5-yl]methyl]-5-cyclopropyl-2-ethylimidazole-4-carboxamide

分子式

C25H22BrF3N4O4S

熔点

密度

1.7g/cm3

分子量

611.431

沸点

707.3ºC at 760mmHg

溶解度

信号词

危险品标志

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基本信息

中文名称

沙普立沙坦

英文名称

3-[[3-bromo-2-[2-(trifluoromethylsulfonylamino)phenyl]-1-benzofuran-5-yl]methyl]-5-cyclopropyl-2-ethylimidazole-4-carboxamide

中文别名

英文别名

Saprisartan、Saprisartan potassium

CAS号

146623-69-0

分子式

C25H22BrF3N4O4S

分子量

611.431

精确质量

610.05

PSA

128.6

LOGP

7.7614

物化性质

密度

1.7g/cm3

沸点

707.3ºC at 760mmHg

闪点

381.5ºC

折射率

1.686

蒸汽压

7.48E-20mmHg at 25°C

合成路线

530-62-1

N,N'-羰基二咪唑

146623-68-9

1-[[3-bromo-2-[2-[[(trifluoromethyl)sulfonyl]amino]phenyl]-5-benzofuranyl]methyl]-4-cyclopropyl-2-ethyl-1H-imidazole-5-carboxylic acid

上游原料

ethyl 1-[[3-bromo-2-[2-[[(trifluoromethyl)sulfonyl]amino]phenyl]-5-benzofuranyl]methyl]-4-cyclopropyl-2-ethyl-1H-imidazole-5-carboxylate

530-62-1

N,N'-羰基二咪唑

146623-68-9

1-[[3-bromo-2-[2-[[(trifluoromethyl)sulfonyl]amino]phenyl]-5-benzofuranyl]methyl]-4-cyclopropyl-2-ethyl-1H-imidazole-5-carboxylic acid

146014-02-0

ethyl 4-cyclopropyl-2-ethyl-1H-imidazole-5-carboxylate

1025993-01-4

ethyl 3-cyclopropyl-2-nitro-3-oxopropanoate

146624-44-4

1,1-dimethylethyl <2-(3-bromo-5-methyl-2-benzofuranyl)phenyl>carbamate

上游原料

ethyl 1-[[3-bromo-2-[2-[[(trifluoromethyl)sulfonyl]amino]phenyl]-5-benzofuranyl]methyl]-4-cyclopropyl-2-ethyl-1H-imidazole-5-carboxylate N,N'-羰基二咪唑 1-[[3-bromo-2-[2-[[(trifluoromethyl)sulfonyl]amino]phenyl]-5-benzofuranyl]methyl]-4-cyclopropyl-2-ethyl-1H-imidazole-5-carboxylic acid ethyl 4-cyclopropyl-2-ethyl-1H-imidazole-5-carboxylate ethyl 3-cyclopropyl-2-nitro-3-oxopropanoate 1,1-dimethylethyl <2-(3-bromo-5-methyl-2-benzofuranyl)phenyl>carbamate ethyl 1-<<3-bromo-2-(2-aminophenyl)-5-benzofuranyl>methyl>-4-cyclopropyl-2-ethyl-1H-imidazole-5-carboxylate 2-(3-bromo-5-methyl-2-benzofuranyl)benzoic acid 5-甲基苯并呋喃邻溴苯甲酸甲酯 1,1-dimethylethyl (2-(3-bromo-5-(bromomethyl)-2-benzofuranyl)phenyl)carbamate 3-环丙基-3-羰基-丙酸乙酯 ethyl 1-<<3-bromo-2-<2-<<(1,1-dimethylethoxy)carbonyl>amino>phenyl>-5-benzofuranyl>methyl>-4-cyclopropyl-2-ethyl-1H-imidazole-5-carboxylate