利匹沙坦

CAS号：148504-51-2

英文名：5-methyl-7-propyl-8-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]-3H-[1,2,4]triazolo[1,5-c]pyrimidin-2-one

分子式

C23H22N8O

熔点

密度

1.42g/cm3

分子量

426.474

沸点

溶解度

信号词

危险品标志

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基本信息

中文名称

利匹沙坦

英文名称

5-methyl-7-propyl-8-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]-3H-[1,2,4]triazolo[1,5-c]pyrimidin-2-one

中文别名

英文别名

UP 269-6、Ripisartan、UNII-7LQ7OQP653

CAS号

148504-51-2

分子式

C23H22N8O

分子量

426.474

精确质量

426.192

PSA

117.51

LOGP

3.1164

编号系统

UNII

7LQ7OQP653

物化性质

密度

1.42g/cm3

折射率

1.747

合成路线

148475-98-3

4'-((5-methyl-2-oxo-7-propyl-2,3-dihydro-[1,2,4]triazolo[1,5-c]pyrimidin-8-yl)methyl)-[1,1'-biphenyl]-2-carbonitrile

上游原料

5-[(2'-cyanobiphenyl-4-yl)methyl]-4-hydrazino-2-methyl-6-n-propylpyrimidine

135689-67-7

5-[(2'-cyanobiphenyl-4-yl)methyl]-2-methyl-6-n-propylpyrimidin-4(3H)-one

137860-26-5

ethyl 2-[(2'-cyanobiphenyl-4-yl)methyl]-3-oxohexanoate

148475-98-3

4'-((5-methyl-2-oxo-7-propyl-2,3-dihydro-[1,2,4]triazolo[1,5-c]pyrimidin-8-yl)methyl)-[1,1'-biphenyl]-2-carbonitrile

上游原料

5-[(2'-cyanobiphenyl-4-yl)methyl]-4-hydrazino-2-methyl-6-n-propylpyrimidine 5-[(2'-cyanobiphenyl-4-yl)methyl]-2-methyl-6-n-propylpyrimidin-4(3H)-one ethyl 2-[(2'-cyanobiphenyl-4-yl)methyl]-3-oxohexanoate 丁酰乙酸乙酯 2-氰基-4'-溴甲基联苯 4-chloro-5-[(2'-cyanobiphenyl-4-yl)methyl]-2-methyl-6-n-propylpyrimidine