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普瑞巴林

普瑞巴林

CAS号：148553-50-8

英文名：pregabalin

分子式

C8H17NO2

熔点

194-196ºC

密度

0.997 g/cm3

分子量

159.226

沸点

274ºC at 760 mmHg

溶解度

信号词

Danger

危险品标志

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化合物简介

S-Enantiomer of Pregabalin. A GABA analogue used as an anticonvulsant. Anxiolytic analgesic used to treat peripheral neuropathic pain and fibromyalgia.

基本信息

中文名称

普瑞巴林

英文名称

pregabalin

中文别名

(3S)-3-氨甲基-5-甲基己酸、(S)-3-氨甲基-5-甲基己酸

英文别名

Pregabalin、(S)-3-(Aminomethyl)-5-methylhexanoic acid CI-1008 PD-144723、Pregablin、Lyrica、(S)-3-(Aminomethyl)-5-methylhexanoic acid、PREDNISOLONESODIUMPHOSPHATE

CAS号

148553-50-8

分子式

C8H17NO2

分子量

159.226

精确质量

159.126

PSA

63.32

LOGP

1.7824

编号系统

MDL号

MFCD00917044

物化性质

外观与性状

白色或近乎于白色结晶粉末

密度

0.997 g/cm3

沸点

274ºC at 760 mmHg

熔点

194-196ºC

闪点

119.5ºC

折射率

1.464

蒸汽压

0.00153mmHg at 25°C

安全信息

海关编码

2915900090

危险标志

GHS05, GHS08

信号词

Danger

危险性防范说明

P280; P305 + P351 + P338 + P310

危险性描述

H318; H361

合成路线

共找到2条合成路线 >

(S)-3-azidomethyl-5-methylhexanoic acid

(S)-3-azidomethyl-5-methylhexanoic acid

普瑞巴林

海关数据

共找到8个国家海关数据 >

国家/地区名称	海关编码	更新时间	操作
中国	2922499990	2019-03	查看
美国	2922494050	2019-03	查看
印度	29224990	2019-03	查看
欧盟	29224985	2019-03	查看
英国	2922498590	2019-03	查看
日本	292249010	2019-03	查看
韩国	2922499000	2019-03	查看
加拿大	2922490090	2019-03	查看

上游原料

共找到71个上游原料 >

ethyl 3-(bromomethyl)-5-methylhexanoate

ethyl 3-(bromomethyl)-5-methylhexanoate

(S)-2-bromo-N-(4-methyl-pent-2-enyl)-N-(1-phenyl-ethyl)acetamide

(S)-2-bromo-N-(4-methyl-pent-2-enyl)-N-(1-phenyl-ethyl)acetamide

3-氨甲基-5-甲基己酸

3-氨甲基-5-甲基己酸

(S)-3-(isopropoxycarbonyl-aminomethyl)-5-methyl-hexanoic acid (S)-(-)-1-phenylethylamine salt

(S)-3-(isopropoxycarbonyl-aminomethyl)-5-methyl-hexanoic acid (S)-(-)-1-phenylethylamine salt

tosyl-L-glutamic acid compound with (S)-3-(aminomethyl)-5-methylhexanoic acid (1:1)

tosyl-L-glutamic acid compound with (S)-3-(aminomethyl)-5-methylhexanoic acid (1:1)

3-(氨甲酰甲基)-5-甲基己酸

3-(氨甲酰甲基)-5-甲基己酸

下游产品

共找到2个下游商品 >

(3S)-3-氰基-5-甲基己酸

(3S)-3-氰基-5-甲基己酸

(S)-(+)-3-(aminomethyl)-5-methylhexanoic acid (S)-mandelate

(S)-(+)-3-(aminomethyl)-5-methylhexanoic acid (S)-mandelate

上游原料

ethyl 3-(bromomethyl)-5-methylhexanoate (S)-2-bromo-N-(4-methyl-pent-2-enyl)-N-(1-phenyl-ethyl)acetamide 3-氨甲基-5-甲基己酸 (S)-3-(isopropoxycarbonyl-aminomethyl)-5-methyl-hexanoic acid (S)-(-)-1-phenylethylamine salt tosyl-L-glutamic acid compound with (S)-3-(aminomethyl)-5-methylhexanoic acid (1:1) 3-(氨甲酰甲基)-5-甲基己酸 diethyl 2-[(2S)-4-methyl-1-nitropentan-2-yl]propanedioate (S)-3-cyano-5-methylhexanoic acid salt of cinchonidine (4S)-4-Isobutyldihydro-2(3H)-furanone (S)-2-hydroxy-2-phenylacetic acid compound with 3-(aminomethyl)-5-methylhexanoic acid (1:1) (S)-3-azidomethyl-5-methyl-hexanoic acid ethyl ester (4R)-4-(2-methylprop-1-enyl)pyrrolidin-2-one R-(+)-3-(carbamoylmethyl)-5-methylhexanoic acid sodium salt isopropyl (S)-{4-methyl-2-[(1-methoxycarbonyl)methyl]pentyl}-carbamate 4-甲基-2-氧代戊腈 (S)-(+)-3-aminomethyl-5-methylhexanoic acid (-)-(O,O')-di-p-toluoyl-L-tartaric acid salt benzyl (S)-3-((((benzyloxy)carbonyl)amino)methyl)-5-methylhexanoate benzoyl-L-glutamic acid compound with (S)-3-(aminomethyl)-5-methylhexanoic acid (1:1) 4-甲基-2-戊酮 (S)-3-azidomethyl-5-methylhexanoic acid 5-甲基-3-羰基己酸乙酯 (S)-(+)-5-methyl-3-(nitromethyl)hexanoic acid (R)-3-(羰基甲基)-5-甲基己酸 (4-methylbenzoyl)-L-glutamic acid compound with (S)-3-(aminomethyl)-5-methylhexanoic acid (1:1) 异戊酰氯 (S)-3-(aminomethyl)-5-methyl-N-((S)-1-phenylethyl)hexanamide 2-cyano-4-methylpent-2-enoic acid (S)-pregabalin-(-)-O,O'-dibenzoyl-L-tartrate (S)-3-cyano-5-methylhexanoic acid ethyl ester (R)-(-)-3-(氨甲酰甲基)-5-甲基己酸 3-异丁基戊二酸酐 (-)-(S)-3-(benzyloxycarbonylamino-methyl)-5-methyl-hexanoic acid (3S)-3-氰基-5-甲基己酸 2-cyano-4-methylpentanoic acid pregabalin potassium salt (-)-(S)-3-(benzyloxycarbonylamino-methyl)-5-methyl-hexanoic acid 3-phenyl-allyl ester (4S)-ethyl tetrahydro-4-isobutyl-2-oxofuran-3-carboxylate (S)-5-methyl-3-nitromethyl hexanoic acid ethyl ester (phenylsulfonyl)-L-glutamic acid compound with (S)-3-(aminomethyl)-5-methylhexanoic acid (1:1) (S)-3-(aminomethyl)-N,N-diethyl-5-methylhexanamide (R)-3-((tert-butoxycarbonylamino)methyl)-5-methylhex-4-enoic acid (S)-4-isobutyl-pyrrolidin-2-one Carbamic acid, N-[(2S)-4-methyl-2-[2-oxo-2-[[(1S)-1-phenylethyl]amino]ethyl]pentyl]-, methyl ester (S)-3-(isopropoxycarbonyl-aminomethyl)-5-methyl-hexanoic acid 5-methyl-3-(nitromethyl)hexanoic acid (-)-(R)-3-isobutyl-pentanedioic acid mono-(3-phenyl-allyl) ester (3S,4S)-4-isobutyl-2-oxopyrrolidine-3-carboxylic acid

下游产品

(3S)-3-氰基-5-甲基己酸 (S)-(+)-3-(aminomethyl)-5-methylhexanoic acid (S)-mandelate