百科

tert-butyl N-(6-{[(2R,15R)-7-(benzyloxy)-8-fluoro-4,15,20-trimethyl-3,12-dioxo-13-oxa-4,11-diazatricyclo[14.2.2.16.10]henicosa-1(18),6,8,10(21),16,19-hexaen-2-yl]amino}isoquinolin-1-yl)-N-[(tert-butoxy)carbonyl]carbamate

tert-butyl N-(6-{[(2R,15R)-7-(benzyloxy)-8-fluoro-4,15,20-trimethyl-3,12-dioxo-13-oxa-4,11-diazatricyclo[14.2.2.16.10]henicosa-1(18),6,8,10(21),16,19-hexaen-2-yl]amino}isoquinolin-1-yl)-N-[(tert-butoxy)carbonyl]carbamate

CAS号：1508297-22-0

英文名：tert-butyl N-(6-{[(2R,15R)-7-(benzyloxy)-8-fluoro-4,15,20-trimethyl-3,12-dioxo-13-oxa-4,11-diazatricyclo[14.2.2.16.10]henicosa-1(18),6,8,10(21),16,19-hexaen-2-yl]amino}isoquinolin-1-yl)-N-[(tert-butoxy)carbonyl]carbamate

分子式

C47H52FN5O8

熔点

密度

分子量

833.943

沸点

溶解度

信号词

危险品标志

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基本信息

中文名称

tert-butyl N-(6-{[(2R,15R)-7-(benzyloxy)-8-fluoro-4,15,20-trimethyl-3,12-dioxo-13-oxa-4,11-diazatricyclo[14.2.2.16.10]henicosa-1(18),6,8,10(21),16,19-hexaen-2-yl]amino}isoquinolin-1-yl)-N-[(tert-butoxy)carbonyl]carbamate

英文名称

tert-butyl N-(6-{[(2R,15R)-7-(benzyloxy)-8-fluoro-4,15,20-trimethyl-3,12-dioxo-13-oxa-4,11-diazatricyclo[14.2.2.16.10]henicosa-1(18),6,8,10(21),16,19-hexaen-2-yl]amino}isoquinolin-1-yl)-N-[(tert-butoxy)carbonyl]carbamate

中文别名

英文别名

CAS号

1508297-22-0

分子式

C47H52FN5O8

分子量

833.943

精确质量

833.38

PSA

148.63

LOGP

10.5642

合成路线

共找到4条合成路线 >

3-fluoro-2-hydroxy-5-nitrobenzaldehyde

3-fluoro-2-hydroxy-5-nitrobenzaldehyde

tert-butyl N-(6-{[(2R,15R)-7-(benzyloxy)-8-fluoro-4,15,20-trimethyl-3,12-dioxo-13-oxa-4,11-diazatricyclo[14.2.2.16.10]henicosa-1(18),6,8,10(21),16,19-hexaen-2-yl]amino}isoquinolin-1-yl)-N-[(tert-butoxy)carbonyl]carbamate

tert-butyl N-(6-{[(2R,15R)-7-(benzyloxy)-8-fluoro-4,15,20-trimethyl-3,12-dioxo-13-oxa-4,11-diazatricyclo[14.2.2.16.10]henicosa-1(18),6,8,10(21),16,19-hexaen-2-yl]amino}isoquinolin-1-yl)-N-[(tert-butoxy)carbonyl]carbamate

上游原料

共找到7个上游原料 >

(3-fluoro-2-hydroxy-5-nitro-benzyl)-methyl-carbamic acid tert-butyl ester

(3-fluoro-2-hydroxy-5-nitro-benzyl)-methyl-carbamic acid tert-butyl ester

(R)-(4-(1-((tert-butyldimethylsilyl)oxy)propan-2-yl)-3-methylphenyl)boronic acid

(R)-(4-(1-((tert-butyldimethylsilyl)oxy)propan-2-yl)-3-methylphenyl)boronic acid

(R)-(4-(1-hydroxhydroxyprop-2-yl)-3-methylphenyl)boronic acid

(R)-(4-(1-hydroxhydroxyprop-2-yl)-3-methylphenyl)boronic acid

tert-butyl 5-amino-2-(benzyloxy)-3-fluorobenzyl(methyl)carbamate

tert-butyl 5-amino-2-(benzyloxy)-3-fluorobenzyl(methyl)carbamate

tert-butyl 2-(benzyloxy)-3-fluoro-5-nitrobenzyl(methyl)carbamate

tert-butyl 2-(benzyloxy)-3-fluoro-5-nitrobenzyl(methyl)carbamate

4-(benzyloxy)-3-fluoro-5-((methylamino)methyl)aniline hydrochloride

4-(benzyloxy)-3-fluoro-5-((methylamino)methyl)aniline hydrochloride

下游产品

共找到4个下游商品 >

(2R,15R)-2-[(1-aminoisoquinolin-6-yl)amino]-7-[(1,3-difluoropropan-2-yl)oxy]-8-fluoro-4,15,20-trimethyl-13-oxa-4,11-diazatricyclo[14.2.2.16.10]henicosa-1(18),6,8,10(21),16,19-hexaene-3,12-dione trifluoroacetate

(2R,15R)-2-[(1-aminoisoquinolin-6-yl)amino]-7-[(1,3-difluoropropan-2-yl)oxy]-8-fluoro-4,15,20-trimethyl-13-oxa-4,11-diazatricyclo[14.2.2.16.10]henicosa-1(18),6,8,10(21),16,19-hexaene-3,12-dione trifluoroacetate

1-({[(2R,15R)-2-[(1-aminoisoquinolin-6-yl)amino]-8-fluoro-4,15,20-trimethyl-3,12-dioxo-13-oxa-4,11-diazatricyclo[14.2.2.16.10]henicosa-1(18),6,8,10(21),16,19-hexaen-7-yl]oxy}methyl)cyclopropane-1-carbonitrile trifluoroacetate

1-({[(2R,15R)-2-[(1-aminoisoquinolin-6-yl)amino]-8-fluoro-4,15,20-trimethyl-3,12-dioxo-13-oxa-4,11-diazatricyclo[14.2.2.16.10]henicosa-1(18),6,8,10(21),16,19-hexaen-7-yl]oxy}methyl)cyclopropane-1-carbonitrile trifluoroacetate

(2R,15R)-2-[(1-aminoisoquinolin-6-yl)amino]-8-fluoro-7-[(2S)-2-hydroxypropoxy]-4,15,20-trimethyl-13-oxa-4,11-diazatricyclo[14.2.2.16.10]henicosa-1(18),6,8,10(21),16,19-hexaene-3,12-dione trifluoroacetate

(2R,15R)-2-[(1-aminoisoquinolin-6-yl)amino]-8-fluoro-7-[(2S)-2-hydroxypropoxy]-4,15,20-trimethyl-13-oxa-4,11-diazatricyclo[14.2.2.16.10]henicosa-1(18),6,8,10(21),16,19-hexaene-3,12-dione trifluoroacetate

上游原料

(3-fluoro-2-hydroxy-5-nitro-benzyl)-methyl-carbamic acid tert-butyl ester (R)-(4-(1-((tert-butyldimethylsilyl)oxy)propan-2-yl)-3-methylphenyl)boronic acid (R)-(4-(1-hydroxhydroxyprop-2-yl)-3-methylphenyl)boronic acid tert-butyl 5-amino-2-(benzyloxy)-3-fluorobenzyl(methyl)carbamate tert-butyl 2-(benzyloxy)-3-fluoro-5-nitrobenzyl(methyl)carbamate 4-(benzyloxy)-3-fluoro-5-((methylamino)methyl)aniline hydrochloride 3-fluoro-2-hydroxy-5-nitrobenzaldehyde

下游产品

(2R,15R)-2-[(1-aminoisoquinolin-6-yl)amino]-7-[(1,3-difluoropropan-2-yl)oxy]-8-fluoro-4,15,20-trimethyl-13-oxa-4,11-diazatricyclo[14.2.2.16.10]henicosa-1(18),6,8,10(21),16,19-hexaene-3,12-dione trifluoroacetate 1-({[(2R,15R)-2-[(1-aminoisoquinolin-6-yl)amino]-8-fluoro-4,15,20-trimethyl-3,12-dioxo-13-oxa-4,11-diazatricyclo[14.2.2.16.10]henicosa-1(18),6,8,10(21),16,19-hexaen-7-yl]oxy}methyl)cyclopropane-1-carbonitrile trifluoroacetate (2R,15R)-2-[(1-aminoisoquinolin-6-yl)amino]-8-fluoro-7-[(2S)-2-hydroxypropoxy]-4,15,20-trimethyl-13-oxa-4,11-diazatricyclo[14.2.2.16.10]henicosa-1(18),6,8,10(21),16,19-hexaene-3,12-dione trifluoroacetate