百科

(5R,7R,8S,10R,11R,11aS)-5-acetoxymethyl-7-cyano-10-hydroxymethyl-4-methoxy-13-methyl-5,7,8,9,10,11,11a,12-octahydro-8,11-iminoazepino<1,2-b>isoquinoline

(5R,7R,8S,10R,11R,11aS)-5-acetoxymethyl-7-cyano-10-hydroxymethyl-4-methoxy-13-methyl-5,7,8,9,10,11,11a,12-octahydro-8,11-iminoazepino<1,2-b>isoquinoline

CAS号：152500-64-6

英文名：(5R,7R,8S,10R,11R,11aS)-5-acetoxymethyl-7-cyano-10-hydroxymethyl-4-methoxy-13-methyl-5,7,8,9,10,11,11a,12-octahydro-8,11-iminoazepino<1,2-b>isoquinoline

分子式：C21H27N3O4

分子量：385.457

合成路线

(5R,7R,8S,10R,11R,11aS)-5-(acetoxymethyl)-7-cyano-4-methoxy-13-methyl-5,7,8,9,10,11,11a,12-octahydro-8,11-epiminoazepino[1,2-b]isoquinoline-10-carboxylic (isopropyl carbonic) anhydride

(5R,7R,8S,10R,11R,11aS)-5-(acetoxymethyl)-7-cyano-4-methoxy-13-methyl-5,7,8,9,10,11,11a,12-octahydro-8,11-epiminoazepino[1,2-b]isoquinoline-10-carboxylic (isopropyl carbonic) anhydride

(5R,7R,8S,10R,11R,11aS)-5-acetoxymethyl-7-cyano-10-hydroxymethyl-4-methoxy-13-methyl-5,7,8,9,10,11,11a,12-octahydro-8,11-iminoazepino<1,2-b>isoquinoline

(5R,7R,8S,10R,11R,11aS)-5-acetoxymethyl-7-cyano-10-hydroxymethyl-4-methoxy-13-methyl-5,7,8,9,10,11,11a,12-octahydro-8,11-iminoazepino<1,2-b>isoquinoline

2-<(4R,5R)-5-benzyloxymethyl-2,2-dimethyl-1,3-dioxolane-4-carbonyl>-3-methylanisole

2-<(4R,5R)-5-benzyloxymethyl-2,2-dimethyl-1,3-dioxolane-4-carbonyl>-3-methylanisole

(5R,7R,8S,10R,11R,11aS)-5-acetoxymethyl-7-cyano-10-hydroxymethyl-4-methoxy-13-methyl-5,7,8,9,10,11,11a,12-octahydro-8,11-iminoazepino<1,2-b>isoquinoline

(5R,7R,8S,10R,11R,11aS)-5-acetoxymethyl-7-cyano-10-hydroxymethyl-4-methoxy-13-methyl-5,7,8,9,10,11,11a,12-octahydro-8,11-iminoazepino<1,2-b>isoquinoline

2-<(4S,5R)-5-methoxymethoxymethyl-2,2-dimethyl-1,3-dioxolane-4-carbonyl>-3-methylanisole

2-<(4S,5R)-5-methoxymethoxymethyl-2,2-dimethyl-1,3-dioxolane-4-carbonyl>-3-methylanisole

(5R,7R,8S,10R,11R,11aS)-5-acetoxymethyl-7-cyano-10-hydroxymethyl-4-methoxy-13-methyl-5,7,8,9,10,11,11a,12-octahydro-8,11-iminoazepino<1,2-b>isoquinoline

(5R,7R,8S,10R,11R,11aS)-5-acetoxymethyl-7-cyano-10-hydroxymethyl-4-methoxy-13-methyl-5,7,8,9,10,11,11a,12-octahydro-8,11-iminoazepino<1,2-b>isoquinoline

上游原料

2-<(4R,5R)-5-benzyloxymethyl-2,2-dimethyl-1,3-dioxolane-4-carbonyl>-3-methylanisole 2-<(4S,5R)-5-methoxymethoxymethyl-2,2-dimethyl-1,3-dioxolane-4-carbonyl>-3-methylanisole (5R,7R,8S,10R,11R,11aS)-5-(acetoxymethyl)-7-cyano-4-methoxy-13-methyl-5,7,8,9,10,11,11a,12-octahydro-8,11-epiminoazepino[1,2-b]isoquinoline-10-carboxylic (isopropyl carbonic) anhydride

下游产品