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trichostatin D

trichostatin D

CAS号：157479-37-3

英文名：trichostatin D

分子式

C23H32N2O8

熔点

131 - 135 °C

密度

分子量

464.509

沸点

溶解度

信号词

危险品标志

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基本信息

中文名称

trichostatin D

英文名称

trichostatin D

中文别名

英文别名

(2E,4E)-(R)-7-(4-Dimethylamino-phenyl)-4,6-dimethyl-7-oxo-hepta-2,4-dienoic acid ((2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-hydroxymethyl-tetrahydro-pyran-2-yloxy)-amide

CAS号

157479-37-3

分子式

C23H32N2O8

分子量

464.509

精确质量

464.216

PSA

148.79

LOGP

0.3125

物化性质

熔点

131 - 135 °C

合成路线

(R)-3-[(E)-(4R,5R)-5-(4-Bromo-phenyl)-5-(tert-butyl-dimethyl-silanyloxy)-2,4-dimethyl-pent-2-enoyl]-4-isopropyl-oxazolidin-2-one

(R)-3-[(E)-(4R,5R)-5-(4-Bromo-phenyl)-5-(tert-butyl-dimethyl-silanyloxy)-2,4-dimethyl-pent-2-enoyl]-4-isopropyl-oxazolidin-2-one

trichostatin D

上游原料

共找到8个上游原料 >

2,3,4,6-O-四苄基-D-葡萄糖

2,3,4,6-O-四苄基-D-葡萄糖

O-[(2R,3R,4S,5R,6R)-3,4,5-Tris-(tert-butyl-dimethyl-silanyloxy)-6-(tert-butyl-dimethyl-silanyloxymethyl)-tetrahydro-pyran-2-yl]-hydroxylamine

O-[(2R,3R,4S,5R,6R)-3,4,5-Tris-(tert-butyl-dimethyl-silanyloxy)-6-(tert-butyl-dimethyl-silanyloxymethyl)-tetrahydro-pyran-2-yl]-hydroxylamine

(3aR,7aS)-2-[(2R,3R,4S,5R,6R)-3,4,5-Tris-(tert-butyl-dimethyl-silanyloxy)-6-(tert-butyl-dimethyl-silanyloxymethyl)-tetrahydro-pyran-2-yloxy]-hexahydro-isoindole-1,3-dione

(3aR,7aS)-2-[(2R,3R,4S,5R,6R)-3,4,5-Tris-(tert-butyl-dimethyl-silanyloxy)-6-(tert-butyl-dimethyl-silanyloxymethyl)-tetrahydro-pyran-2-yloxy]-hexahydro-isoindole-1,3-dione

(3aR,7aS)-2-((2R,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-hydroxymethyl-tetrahydro-pyran-2-yloxy)-hexahydro-isoindole-1,3-dione

(3aR,7aS)-2-((2R,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-hydroxymethyl-tetrahydro-pyran-2-yloxy)-hexahydro-isoindole-1,3-dione

(4R,1'E,3'E)-(-1'-{[tert-butyl(dimethyl)silyl]oxy}-2'-methyl-1',3'-pentadienyl)-4-isopropyl-1,3-oxazolidin-2-one

(4R,1'E,3'E)-(-1'-{[tert-butyl(dimethyl)silyl]oxy}-2'-methyl-1',3'-pentadienyl)-4-isopropyl-1,3-oxazolidin-2-one

(R)-3-[(E)-(4R,5R)-5-(4-Bromo-phenyl)-5-hydroxy-2,4-dimethyl-pent-2-enoyl]-4-isopropyl-oxazolidin-2-one

(R)-3-[(E)-(4R,5R)-5-(4-Bromo-phenyl)-5-hydroxy-2,4-dimethyl-pent-2-enoyl]-4-isopropyl-oxazolidin-2-one

上游原料

2,3,4,6-O-四苄基-D-葡萄糖 O-[(2R,3R,4S,5R,6R)-3,4,5-Tris-(tert-butyl-dimethyl-silanyloxy)-6-(tert-butyl-dimethyl-silanyloxymethyl)-tetrahydro-pyran-2-yl]-hydroxylamine (3aR,7aS)-2-[(2R,3R,4S,5R,6R)-3,4,5-Tris-(tert-butyl-dimethyl-silanyloxy)-6-(tert-butyl-dimethyl-silanyloxymethyl)-tetrahydro-pyran-2-yloxy]-hexahydro-isoindole-1,3-dione (3aR,7aS)-2-((2R,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-hydroxymethyl-tetrahydro-pyran-2-yloxy)-hexahydro-isoindole-1,3-dione (4R,1'E,3'E)-(-1'-{[tert-butyl(dimethyl)silyl]oxy}-2'-methyl-1',3'-pentadienyl)-4-isopropyl-1,3-oxazolidin-2-one (R)-3-[(E)-(4R,5R)-5-(4-Bromo-phenyl)-5-hydroxy-2,4-dimethyl-pent-2-enoyl]-4-isopropyl-oxazolidin-2-one (R)-3-[(E)-(4R,5R)-5-(4-Bromo-phenyl)-5-(tert-butyl-dimethyl-silanyloxy)-2,4-dimethyl-pent-2-enoyl]-4-isopropyl-oxazolidin-2-one (3aR,7aS)-2-((2R,3R,4S,5R,6R)-3,4,5-Tris-benzyloxy-6-benzyloxymethyl-tetrahydro-pyran-2-yloxy)-hexahydro-isoindole-1,3-dione