化合物简介
Nelfinavir (brand name Viracept) is an antiretroviral drug used in the treatment of the human immunodeficiency virus (HIV). Nelfinavir belongs to the class of drugs known as protease inhibitors (PIs) and like other PIs is almost always used in combination with other antiretroviral drugs.
基本信息
中文名称
奈非那韦
英文名称
nelfinavir
中文别名
娜芙维亚、2-[(2R,3R)-2-羟基-3-[(3-羟基-2-甲基苯甲酰)氨基]-4-(苯基硫)丁基]-(3S,4aS,8aS)-N-叔丁基十氢异喹啉-3-甲酰胺
英文别名
AG1343、Viracept (TN)、UNII-HO3OGH5D7I、(3S,4aS,8aS)-N-tert-butyl-2-[(2R,3R)-2-hydroxy-3-[(3-hydroxy-2-methylbenzoyl)amino]-4-phenylsulfanylbutyl]-3,4,4a,5,6,7,8,8a-octahydro-1H-isoquinoline-3-carboxamide、[3H]-Nelfinavir、Nelfinavir Monomethane Sulfonate、[3S-(3R*,4AR*,8AR*,2\'S*,3\'S*)]-2-[2\'-Hydroxy-3\'-phenylthiomethyl-4\'-aza-5\'-oxo-5\'-(2\'\'-methyl-3\'\'-hydroxyphenyl)pentyl]decahydroisoquinoline-3-N-t-butylcarboxamide、(3S,4AS,8AS)-2-[(2R,3R)-2-hydroxy-3-(3-hydroxy-2-methylbenzoylamino)-4-phenylthiobutyl]decahydroisoquinoline-3-carboxylic acid t-butylamide、[14C]-Nelfinavir、Viracept、VRX496、Nelfinavir (INN)、1ohr
CAS号
159989-64-7
分子式
C33H49N3O7S2
分子量
663.888
精确质量
663.301
PSA
189.95
LOGP
6.0521
编号系统
UNII
HO3OGH5D7I
物化性质
外观与性状
白色至灰白色结晶粉末
密度
1.22g/cm3
沸点
786.8ºC at 760 mmHg
闪点
429.7ºC
折射率
1.618
蒸汽压
4.38E-26mmHg at 25°C
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