化合物简介
Bendamustine (INN, trade names Treakisym, Ribomustin, Levact and Treanda; also known as SDX-105) is a nitrogen mustard used in the treatment of chronic lymphocytic leukemia and lymphomas. It belongs to the family of drugs called alkylating agents. It is also being studied for the treatment of sarcoma. It is also being investigated in phase II trials for the non-cancer treatment of AL amyloidosis.
基本信息
中文名称
宾达氮芥
英文名称
4-[5-[bis(2-chloroethyl)amino]-1-methylbenzimidazol-2-yl]butanoic acid
中文别名
4-[5-[双(2-氯乙基)氨基]-1-甲基苯并咪唑-2-基]丁酸
英文别名
4-[5-[bis(2-chloroethyl)amino]-1-methyl-1H-benzimidazol-2-yl]butanoic acid、Bendamustina [Spanish]、Bendamustin、4-{5-[bis-(2-chloro-ethyl)-amino]-1-methyl-1H-benzoimidazol-2-yl}-butyric acid、Bendamustinum [Latin]、4-{5-[bis(2-chloroethyl)amino]-1-methyl-2-benzimidazolyl} butyric acid、UNII-9266D9P3PQ、Bendamustine (INN)、SDX 105、4-<1-Methyl-5-<bis(2-chlorethyl)amino>benzimidazolyl-(2)>butansaeure、Treanda (TN)
CAS号
16506-27-7
分子式
C16H21Cl2N3O2
分子量
358.263
精确质量
357.101
PSA
58.36
LOGP
3.2646
物化性质
密度
1.31 g/cm3
沸点
585.2ºC at 760 mmHg
折射率
1.599
蒸汽压
1.55E-14mmHg at 25°C
安全信息
海关编码
2933990090
上游原料
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